Autores
Montserrat Fitó, Mònica Guxens, Dolores Corella, Guillermo Sáez, Ramón Estruch, Rafael De La Torre, Francesc Francés, Carmen Cabezas, María del Carmen López-Sabater, Jaume Marrugat, Ana García-Arellano, Fernando Arós, Valentina Ruiz-Gutierrez, Emilio Ros, Jordi Salas-Salvadó, Miquel Fiol, Rosa Solá, María-Isabel Covas, PREDIMED Study Investigators
Fecha de publicación
2007/6/11
Revista
Archives of internal medicine
Volumen
167
Número
11
Páginas
1195-1203
Editor
American Medical Association
Descripción
Background
Despite the richness in antioxidants of the Mediterranean diet, to our knowledge, no randomized controlled trials have assessed its effect on in vivo lipoprotein oxidation.
Methods
A total of 372 subjects at high cardiovascular risk (210 women and 162 men; age range, 55-80 years), who were recruited into a large, multicenter, randomized, controlled, parallel-group clinical trial (the Prevención con Dieta Mediterránea [PREDIMED] Study) directed at testing the efficacy of the traditional Mediterranean diet (TMD) on the primary prevention of coronary heart disease, were assigned to a low-fat diet (n = 121) or one of 2 TMDs (TMD + virgin olive oil or TMD + nuts). The TMD participants received nutritional education and either free virgin olive oil for all the family (1 L/wk) or free nuts (30 g/d). Diets were ad libitum. Changes in oxidative stress markers were evaluated at 3 months.
Results
After the 3-month …
Citas totales
Artículos de Google Académico
M Fitó, M Guxens, D Corella, G Sáez, R Estruch… - Archives of internal medicine, 2007