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The chytrid fungus Batrachochytrium dendrobatidis was detected in five populations of Pseudacris hypochondriaca curta, an endemic treefrog fully dependent on desert oases in Baja California Sur, Mexico. Prevalence of the fungus varied among oases with values of 8, 31, 42, 60, and 100% for populations sampled. Oases with higher prevalence were inhabited by exotic species such as American bullfrogs (Lithobates catesbeianus) and crayfish (Procambarus clarkii). These observations are the first of B. dendrobatidis in amphibians from lowland (<100 m) arid environments in Mexico.