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A retrospective study was carried out to assess the possibility of using daily weight gain in first-season grazing cattle (FSG) as a marker for treatment decisions to prevent parasite-induced losses caused by gastrointestinal (GI) nematodes. This is intended as a proof of concept for using targeted selective treatments (TSTs) in the control of veterinary parasites. Historical data were combined from three independent grazing trials in Sweden, each of which was repeated over 2–3 years, in order to investigate the influences of parasites on the performance of FSG cattle subjected to different levels of parasite control. In general, the different trials and years produced congruent results. There was a good positive linear relationship between daily weight gains (Dwgt) registered around housing and those recorded in the middle of the grazing season (r² = 0.54) but not between early-season Dwgt and housing Dwgt. The latter …