Autores
Rajnish Gupta, Manas Mathur, Vijay K Bajaj, Pawan Katariya, Sunita Yadav, Raka Kamal, Radhey S Gupta
Fecha de publicación
2012/6
Revista
Journal of diabetes
Volumen
4
Número
2
Páginas
164-171
Editor
Blackwell Publishing Ltd
Descripción
Background: Moringa oleifera, a widely cultivated species in India, is an exceptionally nutritious vegetable with a variety of potential uses in treating rheumatism, venomous bites, and microbial infections. In the present study, we investigated the antidiabetic and antioxidant effects of methanol extracts of M. oleifera pods (MOMtE) in streptozotocin (STZ)‐induced diabetic albino rats.
Methods: Diabetic rats were treated with 150 or 300 mg/kg MOMtE for 21 days and the antidiabetic effects of the extract were evaluated by measuring changes in biochemical parameters in the serum and pancreatic tissue. Two phytoconstituents, namely quercetin and kaempferol, were isolated from the MOMtE extract and their structures were determined using nuclear magnetic resonance and infrared spectroscopy.
Results: The progression of diabetes was significantly reduced after MOMtE treatment. In treated rats, both doses of …
Artículos de Google Académico
R Gupta, M Mathur, VK Bajaj, P Katariya, S Yadav… - Journal of diabetes, 2012