Autores
Rosario Miralles, Philip J Gerrish, Andrés Moya, Santiago F Elena
Fecha de publicación
1999/9/10
Revista
Science
Volumen
285
Número
5434
Páginas
1745-1747
Editor
American Association for the Advancement of Science
Descripción
In asexual populations, beneficial mutations that occur in different lineages compete with one another. This phenomenon, known as clonal interference, ensures that those beneficial mutations that do achieve fixation are of large effect. Clonal interference also increases the time between fixations, thereby slowing the adaptation of asexual populations. The effects of clonal interference were measured in the asexual RNA virus vesicular stomatitis virus; rates and average effects of beneficial mutations were quantified.
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