Autores
CG Caraguel, R Vanderstichel
Fecha de publicación
2013/3/6
Revista
Evidence-based medicine
Descripción
In 1975, Fagan published a nomogram to help practitioners determine, without the use of a calculator or computer, the probability of a patient truly having a condition of interest given a particular test result. Nomograms are very useful for bedside interpretations of test results, as no test is perfect. However, the practicality of Fagan9s nomogram is limited by its use of the likelihood ratio (LR), a parameter not commonly reported in the evaluation studies of diagnostic tests. The LR reflects the direction and strength of evidence provided by a test result and can be computed from the conventional diagnostic sensitivity (DSe) and specificity (DSp) of the test. This initial computation is absent in Fagan9s nomogram, making it impractical for routine use. We have seamlessly integrated the initial step to compute the LR and the resulting two-step nomogram allows the user to quickly interpret the outcome of a test. With the addition …
Artículos de Google Académico
The two-step Fagan's nomogram: ad hoc interpretation of a diagnostic test result without calculation
CGB Caraguel, R Vanderstichel - BMJ Evidence-Based Medicine, 2013