| Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids JD Leuppi, CM Salome, CR Jenkins, SD Anderson, WEI Xuan, GB Marks, ... American journal of respiratory and critical care medicine 163 (2), 406-412, 2001 | 345 | 2001 |
| Production methods for nanodrug particles using the bottom-up approach HK Chan, PCL Kwok Advanced drug delivery reviews 63 (6), 406-416, 2011 | 287 | 2011 |
| Nano spray drying: a novel method for preparing protein nanoparticles for protein therapy SH Lee, D Heng, WK Ng, HK Chan, RBH Tan International journal of pharmaceutics 403 (1-2), 192-200, 2011 | 279 | 2011 |
| Micronization by rapid expansion of supercritical solutions to enhance the dissolution rates of poorly water-soluble pharmaceuticals M Charoenchaitrakool, F Dehghani, NR Foster, HK Chan Industrial & engineering chemistry research 39 (12), 4794-4802, 2000 | 269 | 2000 |
| Use of solid corrugated particles to enhance powder aerosol performance NYK Chew, HK Chan Pharmaceutical Research 18 (11), 1570-1577, 2001 | 230 | 2001 |
| How much particle surface corrugation is sufficient to improve aerosol performance of powders? NYK Chew, P Tang, HK Chan, JA Raper Pharmaceutical Research 22 (1), 148-152, 2005 | 195 | 2005 |
| Mucociliary clearance in patients with cystic fibrosis and in normal subjects. JA Regnis, M Robinson, DL Bailey, P Cook, P Hooper, HK Chan, I Gonda, ... American journal of respiratory and critical care medicine 150 (1), 66-71, 1994 | 191 | 1994 |
| The effect of inhaled mannitol on bronchial mucus clearance in cystic fibrosis patients: a pilot study M Robinson, E Daviskas, S Eberl, J Baker, HK Chan, SD Anderson, ... European Respiratory Journal 14 (3), 678-685, 1999 | 184 | 1999 |
| Formation, characterization, and fate of inhaled drug nanoparticles J Zhang, L Wu, HK Chan, W Watanabe Advanced drug delivery reviews 63 (6), 441-455, 2011 | 180 | 2011 |
| Effect of design on the performance of a dry powder inhaler using computational fluid dynamics. Part 1: Grid structure and mouthpiece length MS Coates, DF Fletcher, HK Chan, JA Raper Journal of pharmaceutical sciences 93 (11), 2863-2876, 2004 | 162 | 2004 |
| Novel alternative methods for the delivery of drugs for the treatment of asthma HK Chan, NYK Chew Advanced drug delivery reviews 55 (7), 793-805, 2003 | 161 | 2003 |
| Pulmonary delivery of therapeutic siRNA JKW Lam, W Liang, HK Chan Advanced drug delivery reviews 64 (1), 1-15, 2012 | 160 | 2012 |
| Mannitol as a challenge test to identify exercise-induced bronchoconstriction in elite athletes K Holzer, SD Anderson, HK Chan, J Douglass American journal of respiratory and critical care medicine 167 (4), 534-537, 2003 | 159 | 2003 |
| A simple relationship between dielectric constant of mixed solvents with solvent composition and temperature A Jouyban, S Soltanpour, HK Chan International journal of pharmaceutics 269 (2), 353-360, 2004 | 157 | 2004 |
| Spray dried powders and powder blends of recombinant human deoxyribonuclease (rhDNase) for aerosol delivery HK Chan, A Clark, I Gonda, M Mumenthaler, C Hsu Pharmaceutical Research 14 (4), 431-437, 1997 | 156 | 1997 |
| Mathematical representation of solute solubility in supercritical carbon dioxide using empirical expressions A Jouyban, HK Chan, NR Foster The Journal of supercritical fluids 24 (1), 19-35, 2002 | 155 | 2002 |
| Feasibility of preparing nanodrugs by high-gravity reactive precipitation JF Chen, MY Zhou, L Shao, YY Wang, J Yun, NYK Chew, HK Chan International journal of pharmaceutics 269 (1), 267-274, 2004 | 151 | 2004 |
| Effect of amino acids on the dispersion of disodium cromoglycate powders NYK Chew, BY Shekunov, HHY Tong, AHL Chow, C Savage, J Wu, ... Journal of pharmaceutical sciences 94 (10), 2289-2300, 2005 | 144 | 2005 |
| Nanodrugs: pharmacokinetics and safety S Onoue, S Yamada, HK Chan International journal of nanomedicine 9, 1025, 2014 | 140 | 2014 |
| Influence of air flow on the performance of a dry powder inhaler using computational and experimental analyses MS Coates, HK Chan, DF Fletcher, JA Raper Pharmaceutical research 22 (9), 1445-1453, 2005 | 137 | 2005 |
