| Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy D Finzi, M Hermankova, T Pierson, LM Carruth, C Buck, RE Chaisson, ... Science 278 (5341), 1295-1300, 1997 | 2829 | 1997 |
| Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy D Finzi, J Blankson, JD Siliciano, JB Margolick, K Chadwick, T Pierson, ... Nature medicine 5 (5), 512, 1999 | 2103 | 1999 |
| Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection TW Chun, L Carruth, D Finzi, X Shen, JA DiGiuseppe, H Taylor, ... Nature 387 (6629), 183, 1997 | 2085 | 1997 |
| Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells JD Siliciano, J Kajdas, D Finzi, TC Quinn, K Chadwick, JB Margolick, ... Nature medicine 9 (6), 727, 2003 | 1377 | 2003 |
| Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure YC Ho, L Shan, NN Hosmane, J Wang, SB Laskey, DIS Rosenbloom, ... Cell 155 (3), 540-551, 2013 | 784 | 2013 |
| The challenge of viral reservoirs in HIV-1 infection JN Blankson, D Persaud, RF Siliciano Annual review of medicine 53 (1), 557-593, 2002 | 752 | 2002 |
| In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency TW Chun, D Finzi, J Margolick, K Chadwick, D Schwartz, RF Siliciano Nature medicine 1 (12), 1284, 1995 | 737 | 1995 |
| Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation L Shan, K Deng, NS Shroff, CM Durand, SA Rabi, HC Yang, H Zhang, ... Immunity 36 (3), 491-501, 2012 | 621 | 2012 |
| Reservoirs for HIV-1: mechanisms for viral persistence in the presence of antiviral immune responses and antiretroviral therapy T Pierson, J McArthur, RF Siliciano Annual review of immunology 18 (1), 665-708, 2000 | 599 | 2000 |
| A soluble CD4 protein selectively inhibits HIV replication and syncytium formation RE Hussey, NE Richardson, M Kowalski, NR Brown, HC Chang, ... Nature 331 (6151), 78, 1988 | 493 | 1988 |
| Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy JB Dinoso, SY Kim, AM Wiegand, SE Palmer, SJ Gange, L Cranmer, ... Proceedings of the National Academy of Sciences 106 (23), 9403-9408, 2009 | 442 | 2009 |
| Analysis of host-virus interactions in AIDS with anti-gp120 T cell clones: effect of HIV sequence variation and a mechanism for CD4+ cell depletion RF Siliciano, T Lawton, C Knall, RW Karr, P Berman, T Gregory, ... Cell 54 (4), 561-575, 1988 | 422 | 1988 |
| Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies S Eriksson, EH Graf, V Dahl, MC Strain, SA Yukl, ES Lysenko, RJ Bosch, ... PLoS pathogens 9 (2), e1003174, 2013 | 418 | 2013 |
| HIV latency RF Siliciano, WC Greene Cold Spring Harbor perspectives in medicine 1 (1), a007096, 2011 | 417 | 2011 |
| Intermittent HIV-1 viremia (Blips) and drug resistance in patients receiving HAART RE Nettles, TL Kieffer, P Kwon, D Monie, Y Han, T Parsons, ... Jama 293 (7), 817-829, 2005 | 407 | 2005 |
| Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating … JR Bailey, AR Sedaghat, T Kieffer, T Brennan, PK Lee, M Wind-Rotolo, ... Journal of virology 80 (13), 6441-6457, 2006 | 396 | 2006 |
| Control of HIV despite the discontinuation of antiretroviral therapy J Lisziewicz, E Rosenberg, J Lieberman, H Jessen, L Lopalco, R Siliciano, ... New England Journal of Medicine 340 (21), 1683-1683, 1999 | 385 | 1999 |
| Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations K Deng, M Pertea, A Rongvaux, L Wang, CM Durand, G Ghiaur, J Lai, ... Nature 517 (7534), 381, 2015 | 353 | 2015 |
| New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo CK Bullen, GM Laird, CM Durand, JD Siliciano, RF Siliciano Nature medicine 20 (4), 425, 2014 | 348 | 2014 |
| Activation of cytolytic T lymphocyte and natural killer cell function through the T11 sheep erythrocyte binding protein RF Siliciano, JC Pratt, RE Schmidt, J Ritz, EL Reinherz Nature 317 (6036), 428, 1985 | 341 | 1985 |