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| Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. MA Nauck, MM Heimesaat, C Orskov, JJ Holst, R Ebert, W Creutzfeldt The Journal of clinical investigation 91 (1), 301-307, 1993 | 1555 | 1993 |
| Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: a parallel-group study M Zander, S Madsbad, JL Madsen, JJ Holst The Lancet 359 (9309), 824-830, 2002 | 1511 | 2002 |
| Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. A Flint, A Raben, A Astrup, JJ Holst The Journal of clinical investigation 101 (3), 515-520, 1998 | 1351 | 1998 |
| Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients MA Nauck, N Kleine, C Ørskov, JJ Holst, B Willms, W Creutzfeldt Diabetologia 36 (8), 741-744, 1993 | 1175 | 1993 |
| Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients MB Toft-Nielsen, MB Damholt, S Madsbad, LM Hilsted, TE Hughes, ... The Journal of Clinical Endocrinology & Metabolism 86 (8), 3717-3723, 2001 | 1010 | 2001 |
| Antidiabetogenic effect of glucagon-like peptide-1 (7–36) amide in normal subjects and patients with diabetes mellitus M Gutniak, C Ørkov, JJ Holst, B Ahrén, S Efendić New England Journal of Medicine 326 (20), 1316-1322, 1992 | 998 | 1992 |
| Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients T Vilsbøll, T Krarup, CF Deacon, S Madsbad, JJ Holst Diabetes 50 (3), 609-613, 2001 | 986 | 2001 |
| Both subcutaneously and intravenously administered glucagon-like peptide I are rapidly degraded from the NH2-terminus in type II diabetic patients and in healthy subjects CF Deacon, MA Nauck, M Toft-Nielsen, L Pridal, B Willms, JJ Holst Diabetes 44 (9), 1126-1131, 1995 | 958 | 1995 |
| Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans MA Nauck, U Niedereichholz, R Ettler, JJ Holst, C Ørskov, R Ritzel, ... American Journal of Physiology-Endocrinology And Metabolism 273 (5), E981-E988, 1997 | 921 | 1997 |
| Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo CF Deacon, AH Johnsen, JJ Holst The Journal of Clinical Endocrinology & Metabolism 80 (3), 952-957, 1995 | 897 | 1995 |
| Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6. 2 mutations ER Pearson, I Flechtner, PR Njølstad, MT Malecki, SE Flanagan, B Larkin, ... New England Journal of Medicine 355 (5), 467-477, 2006 | 882 | 2006 |
| Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans C Ørskov, L Rabenhøj, A Wettergren, H Kofod, JJ Holst Diabetes 43 (4), 535-539, 1994 | 841 | 1994 |
| Inhibition of gastric inhibitory polypeptide signaling prevents obesity K Miyawaki, Y Yamada, N Ban, Y Ihara, K Tsukiyama, H Zhou, S Fujimoto, ... Nature medicine 8 (7), 738, 2002 | 803 | 2002 |
| Truncated GLP-1 (proglucagon 78–107-amide) inhibits gastric and pancreatic functions in man A Wettergren, B Schjoldager, PE Mortensen, J Myhre, J Christiansen, ... Digestive diseases and sciences 38 (4), 665-673, 1993 | 800 | 1993 |
| Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans JJ Holst, J Gromada American Journal of Physiology-Endocrinology And Metabolism 287 (2), E199-E206, 2004 | 765 | 2004 |
| Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease T Nystrom, MK Gutniak, Q Zhang, F Zhang, JJ Holst, B Ahrén, A Sjoholm American Journal of Physiology-Endocrinology and Metabolism 287 (6), E1209-E1215, 2004 | 720 | 2004 |
| A Meta-Analysis of the Effect of Glucagon-Like Peptide-1 (7–36) Amide on Ad Libitum Energy Intake in Humans C Verdich, A Flint, JP Gutzwiller, E Naslund, C Beglinger, PM Hellstrom, ... The Journal of Clinical Endocrinology & Metabolism 86 (9), 4382-4389, 2001 | 715 | 2001 |
| Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin … B Willms, J Werner, JJ Holst, C Orskov, W Creutzfeldt, MA Nauck The Journal of Clinical Endocrinology & Metabolism 81 (1), 327-332, 1996 | 620 | 1996 |
| Glucagon-like peptide-1-(7–36) amide is transformed to glucagon-like peptide-1-(9–36) amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine … L Hansen, CF Deacon, C Ørskov, JJ Holst Endocrinology 140 (11), 5356-5363, 1999 | 610 | 1999 |
