Charles Craik
Charles Craik
Professor of Pharmaceutical Chemistry, UCSF
Dirección de correo verificada de ucsf.edu - Página principal
TítuloCitado porAño
Structural basis of substrate specificity in the serine proteases
JJ Perona, CS Craik
Protein Science 4 (3), 337-360, 1995
9341995
Lysosomal cysteine proteases: more than scavengers
B Turk, D Turk, V Turk
Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 2000
9292000
Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries
JL Harris, BJ Backes, F Leonetti, S Mahrus, JA Ellman, CS Craik
Proceedings of the National Academy of Sciences 97 (14), 7754-7759, 2000
5302000
Global landscape of HIV–human protein complexes
S Jaeger, P Cimermancic, N Gulbahce, JR Johnson, KE McGovern, ...
Nature 481 (7381), 365, 2012
5072012
Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates
T Takeuchi, JL Harris, W Huang, KW Yan, SR Coughlin, CS Craik
Journal of Biological Chemistry 275 (34), 26333-26342, 2000
4812000
Redesigning trypsin: alteration of substrate specificity
CS Craik, C Largman, T Fletcher, S Roczniak, PJ Barr, R Fletterick, ...
Science 228 (4697), 291-297, 1985
4281985
Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin-and antibody-stimulated glucose uptake and receptor kinase activity
Y Ebina, E Araki, M Taira, F Shimada, M Mori, CS Craik, K Siddle, ...
Proceedings of the National Academy of Sciences 84 (3), 704-708, 1987
4261987
Evolutionary divergence of substrate specificity within the chymotrypsin-like serine protease fold
JJ Perona, CS Craik
Journal of Biological Chemistry 272 (48), 29987-29990, 1997
3481997
The catalytic role of the active site aspartic acid in serine proteases
CS Craik, S Roczniak, C Largman, WJ Rutter
Science 237 (4817), 909-913, 1987
3461987
Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities
Y Choe, F Leonetti, DC Greenbaum, F Lecaille, M Bogyo, D Brömme, ...
Journal of Biological Chemistry 281 (18), 12824-12832, 2006
3362006
Structure-based design of nonpeptide inhibitors specific for the human immunodeficiency virus 1 protease
RL DesJarlais, GL Seibel, ID Kuntz, PS Furth, JC Alvarez, ...
Proceedings of the National Academy of Sciences 87 (17), 6644-6648, 1990
3211990
The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi.
AE Eakin, AA Mills, G Harth, JH McKerrow, CS Craik
Journal of Biological Chemistry 267 (11), 7411-7420, 1992
3151992
Cathepsin G activates protease-activated receptor-4 in human platelets
GR Sambrano, W Huang, T Faruqi, S Mahrus, C Craik, SR Coughlin
Journal of Biological Chemistry 275 (10), 6819-6823, 2000
3112000
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection
S Jäger, DY Kim, JF Hultquist, K Shindo, RS LaRue, E Kwon, M Li, ...
Nature 481 (7381), 371, 2012
3012012
Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and …
T Takeuchi, MA Shuman, CS Craik
Proceedings of the National Academy of Sciences 96 (20), 11054-11061, 1999
2871999
The crystal structure of cruzain: a therapeutic target for Chagas' disease
ME McGrath, AE Eakin, JC Engel, JH McKerrow, CS Craik, RJ Fletterick
Journal of molecular biology 247 (2), 251-259, 1995
2781995
Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin
BJ Backes, JL Harris, F Leonetti, CS Craik, JA Ellman
Nature biotechnology 18 (2), 187, 2000
2712000
Splice junctions: association with variation in protein structure
CS Craik, WJ Rutter, R Fletterick
Science 220 (4602), 1125-1129, 1983
2651983
The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis
S Sprang, T Standing, RJ Fletterick, RM Stroud, J Finer-Moore, NH Xuong, ...
Science 237 (4817), 905-909, 1987
2431987
Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family.
P Vanderslice, SM Ballinger, EK Tam, SM Goldstein, CS Craik, ...
Proceedings of the National Academy of Sciences 87 (10), 3811-3815, 1990
2421990
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20