| Basic local alignment search tool SF Altschul, W Gish, W Miller, EW Myers, DJ Lipman Journal of molecular biology 215 (3), 403-410, 1990 | 81043 | 1990 |
| Gapped BLAST and PSI-BLAST: a new generation of protein database search programs SF Altschul, TL Madden, AA Schäffer, J Zhang, Z Zhang, W Miller, ... Nucleic acids research 25 (17), 3389-3402, 1997 | 71809 | 1997 |
| Identification of FAP locus genes from chromosome 5q21 KW Kinzler, MC Nilbert, LK Su, B Vogelstein, TM Bryan, DB Levy, ... Science 253 (5020), 661-665, 1991 | 2644 | 1991 |
| Detecting subtle sequence signals: a Gibbs sampling strategy for multiple alignment CE Lawrence, SF Altschul, MS Boguski, JS Liu, AF Neuwald, JC Wootton science 262 (5131), 208-214, 1993 | 2268 | 1993 |
| Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences Mammalian Gene Collection (MGC) Program Team Proceedings of the National Academy of Sciences 99 (26), 16899-16903, 2002 | 2167 | 2002 |
| Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes S Karlin, SF Altschul Proceedings of the National Academy of Sciences 87 (6), 2264-2268, 1990 | 2104 | 1990 |
| Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements AA Schäffer, L Aravind, TL Madden, S Shavirin, JL Spouge, YI Wolf, ... Nucleic acids research 29 (14), 2994-3005, 2001 | 1358 | 2001 |
| A workbench for multiple alignment construction and analysis GD Schuler, SF Altschul, DJ Lipman Proteins: Structure, Function, and Bioinformatics 9 (3), 180-190, 1991 | 1125 | 1991 |
| [27] Local alignment statistics SF Altschul, W Gish Methods in enzymology 266, 460-480, 1996 | 1032 | 1996 |
| Applications and statistics for multiple high-scoring segments in molecular sequences S Karlin, SF Altschul Proceedings of the National Academy of Sciences 90 (12), 5873-5877, 1993 | 1015 | 1993 |
| Issues in searching molecular sequence databases SF Altschul, MS Boguski, W Gish, JC Wootton Nature genetics 6 (2), 119, 1994 | 977 | 1994 |
| Amino acid substitution matrices from an information theoretic perspective SF Altschul Journal of molecular biology 219 (3), 555-565, 1991 | 878 | 1991 |
| A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins. P Bork, K Hofmann, P Bucher, AF Neuwald, SF Altschul, EV Koonin The FASEB Journal 11 (1), 68-76, 1997 | 861 | 1997 |
| Protein database searches using compositionally adjusted substitution matrices SF Altschul, JC Wootton, EM Gertz, R Agarwala, A Morgulis, AA Schäffer, ... The FEBS journal 272 (20), 5101-5109, 2005 | 839 | 2005 |
| Iterated profile searches with PSI-BLAST—a tool for discovery in protein databases SF Altschul, EV Koonin Trends in biochemical sciences 23 (11), 444-447, 1998 | 699 | 1998 |
| A tool for multiple sequence alignment DJ Lipman, SF Altschul, JD Kececioglu Proceedings of the National Academy of Sciences 86 (12), 4412-4415, 1989 | 663 | 1989 |
| A public database for gene expression in human cancers A Lal, AE Lash, SF Altschul, V Velculescu, L Zhang, RE McLendon, ... Cancer Research 59 (21), 5403-5407, 1999 | 530 | 1999 |
| Protein database searches for multiple alignments. SF Altschul, DJ Lipman Proceedings of the National Academy of Sciences 87 (14), 5509-5513, 1990 | 514 | 1990 |
| … Functional motifs… EV Koonin, SF Altschul, P Bork Nature genetics 13 (3), 266, 1996 | 509 | 1996 |
| SAGEmap: a public gene expression resource AE Lash, CM Tolstoshev, L Wagner, GD Schuler, RL Strausberg, ... Genome Research 10 (7), 1051-1060, 2000 | 508 | 2000 |