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Yunierkis Perez-Castillo
Yunierkis Perez-Castillo
Verified email at udla.edu.ec
Title
Cited by
Cited by
Year
Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors
MJ Matos, C Teran, Y Perez-Castillo, E Uriarte, L Santana, D Vina
Journal of medicinal chemistry 54 (20), 7127-7137, 2011
1602011
Activity cliffs in drug discovery: Dr Jekyll or Mr Hyde?
M Cruz-Monteagudo, JL Medina-Franco, Y Perez-Castillo, O Nicolotti, ...
Drug Discovery Today 19 (8), 1069-1080, 2014
1562014
HP-Lattice QSAR for dynein proteins: experimental proteomics (2D-electrophoresis, mass spectrometry) and theoretic study of a Leishmania infantum sequence
MA Dea-Ayuela, Y Pérez-Castillo, A Meneses-Marcel, FM Ubeira, ...
Bioorganic & medicinal chemistry 16 (16), 7770-7776, 2008
1122008
Computational chemistry comparison of stable/nonstable protein mutants classification models based on 3D and topological indices
H González‐Díaz, Y Pérez‐castillo, G Podda, E Uriarte
Journal of computational chemistry 28 (12), 1990-1995, 2007
762007
SARS‐CoV‐2, an evolutionary perspective of interaction with human ACE2 reveals undiscovered amino acids necessary for complex stability
V Armijos‐Jaramillo, J Yeager, C Muslin, Y Perez‐Castillo
Evolutionary Applications 13 (9), 2168-2178, 2020
512020
Drugs Repurposing Using QSAR, Docking and Molecular Dynamics for Possible Inhibitors of the SARS-CoV-2 Mpro Protease
E Tejera, CR Munteanu, A López-Cortés, A Cabrera-Andrade, ...
Molecules 25 (21), 5172, 2020
382020
OncoOmics approaches to reveal essential genes in breast cancer: a panoramic view from pathogenesis to precision medicine
A López-Cortés, C Paz-y-Miño, S Guerrero, A Cabrera-Andrade, ...
Scientific reports 10 (1), 5285, 2020
362020
Gene prioritization, communality analysis, networking and metabolic integrated pathway to better understand breast cancer pathogenesis
A López-Cortés, C Paz-y-Miño, A Cabrera-Andrade, SJ Barigye, ...
Scientific reports 8 (1), 16679, 2018
332018
Systemic QSAR and phenotypic virtual screening: chasing butterflies in drug discovery
M Cruz-Monteagudo, S Schürer, E Tejera, Y Perez-Castillo, ...
Drug discovery today 22 (7), 994-1007, 2017
332017
Bioactive terpenes and their derivatives as potential SARS-CoV-2 proteases inhibitors from molecular modeling studies
LRL Diniz, Y Perez-Castillo, HA Elshabrawy, CSMB Filho, DP de Sousa
Biomolecules 11 (1), 74, 2021
322021
Consensus strategy in genes prioritization and combined bioinformatics analysis for preeclampsia pathogenesis
E Tejera, M Cruz-Monteagudo, G Burgos, ME Sánchez, ...
BMC medical genomics 10, 1-19, 2017
292017
Efficient and biologically relevant consensus strategy for Parkinson’s disease gene prioritization
M Cruz-Monteagudo, F Borges, C Paz-y-Miño, M Cordeiro, I Rebelo, ...
BMC medical genomics 9 (1), 1-25, 2016
282016
GA (M) E-QSAR: a novel, fully automatic genetic-algorithm-(meta)-ensembles approach for binary classification in ligand-based drug design
Y Perez-Castillo, C Lazar, J Taminau, M Froeyen, MÁ Cabrera-Pérez, ...
Journal of chemical information and modeling 52 (9), 2366-2386, 2012
272012
Trypanocidal Mechanism of Action and in silico Studies of p-Coumaric Acid Derivatives
SP Lopes, YP Castillo, ML Monteiro, RR Menezes, RN Almeida, ...
International journal of molecular sciences 20 (23), 5916, 2019
242019
From flamingo dance to (desirable) drug discovery: a nature-inspired approach
A Sánchez-Rodríguez, Y Pérez-Castillo, SC Schürer, O Nicolotti, ...
Drug discovery today 22 (10), 1489-1502, 2017
242017
Bacterial beta-ketoacyl-acyl carrier protein synthase III (FabH): an attractive target for the design of new broad-spectrum antimicrobial agents.
YP Castillo, MA Perez
Mini reviews in medicinal chemistry 8 (1), 36-45, 2008
232008
Bioactivity and molecular docking studies of derivatives from cinnamic and benzoic acids
Y Perez-Castillo, TC Lima, AR Ferreira, CR Silva, RS Campos, JBA Neto, ...
BioMed Research International 2020, 1-13, 2020
222020
CompScore: boosting structure-based virtual screening performance by incorporating docking scoring function components into consensus scoring
Y Perez-Castillo, S Sotomayor-Burneo, K Jimenes-Vargas, ...
Journal of chemical information and modeling 59 (9), 3655-3666, 2019
222019
Molecular dynamics and docking simulations as a proof of high flexibility in E. coli FabH and its relevance for accurate inhibitor modeling
Y Pérez-Castillo, M Froeyen, MA Cabrera-Pérez, A Nowé
Journal of computer-aided molecular design 25, 371-393, 2011
222011
NFBTA: a potent cytotoxic agent against glioblastoma
H Turkez, FR Nóbrega, O Ozdemir, CSM Bezerra Filho, RN Almeida, ...
Molecules 24 (13), 2411, 2019
202019
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