| Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity JGM Markle, DN Frank, S Mortin-Toth, CE Robertson, LM Feazel, ... Science 339 (6123), 1084-1088, 2013 | 992 | 2013 |
| Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif (306VQIVYK311) forming β structure M Von Bergen, P Friedhoff, J Biernat, J Heberle, EM Mandelkow, ... Proceedings of the National Academy of Sciences 97 (10), 5129-5134, 2000 | 784 | 2000 |
| Complete nitrification by Nitrospira bacteria H Daims, EV Lebedeva, P Pjevac, P Han, C Herbold, M Albertsen, ... Nature 528 (7583), 504, 2015 | 719 | 2015 |
| Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments A Schneider, J Biernat, M Von Bergen, E Mandelkow, EM Mandelkow Biochemistry 38 (12), 3549-3558, 1999 | 499 | 1999 |
| Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local β-structure M von Bergen, S Barghorn, L Li, A Marx, J Biernat, EM Mandelkow, ... Journal of Biological Chemistry 276 (51), 48165-48174, 2001 | 427 | 2001 |
| Gut microbiota disturbance during antibiotic therapy: a multi-omic approach AE Pérez-Cobas, MJ Gosalbes, A Friedrichs, H Knecht, A Artacho, ... Gut 62 (11), 1591-1601, 2013 | 386 | 2013 |
| Inducible expression of Tau repeat domain in cell models of tauopathy aggregation is toxic to cells but can be reversed by inhibitor drugs I Khlistunova, J Biernat, Y Wang, M Pickhardt, M von Bergen, Z Gazova, ... Journal of Biological Chemistry 281 (2), 1205-1214, 2006 | 341 | 2006 |
| Anthraquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells M Pickhardt, Z Gazova, M von Bergen, I Khlistunova, Y Wang, A Hascher, ... Journal of Biological Chemistry 280 (5), 3628-3635, 2005 | 334 | 2005 |
| A nucleated assembly mechanism of Alzheimer paired helical filaments P Friedhoff, M Von Bergen, EM Mandelkow, P Davies, E Mandelkow Proceedings of the National Academy of Sciences 95 (26), 15712-15717, 1998 | 324 | 1998 |
| Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias S Barghorn, Q Zheng-Fischhöfer, M Ackmann, J Biernat, M Von Bergen, ... Biochemistry 39 (38), 11714-11721, 2000 | 316 | 2000 |
| Functional metaproteome analysis of protein extracts from contaminated soil and groundwater D Benndorf, GU Balcke, H Harms, M Von Bergen The ISME journal 1 (3), 224, 2007 | 293 | 2007 |
| Tau aggregation is driven by a transition from random coil to beta sheet structure M Von Bergen, S Barghorn, J Biernat, EM Mandelkow, E Mandelkow Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1739 (2-3 …, 2005 | 288 | 2005 |
| Global hairpin folding of tau in solution S Jeganathan, M von Bergen, H Brutlach, HJ Steinhoff, E Mandelkow Biochemistry 45 (7), 2283-2293, 2006 | 271 | 2006 |
| Sites of tau important for aggregation populate β-structure and bind to microtubules and polyanions MD Mukrasch, J Biernat, M von Bergen, C Griesinger, E Mandelkow, ... Journal of Biological Chemistry 280 (26), 24978-24986, 2005 | 248 | 2005 |
| Structural principles of tau and the paired helical filaments of Alzheimer’s disease E Mandelkow, M Von Bergen, J Biernat, EM Mandelkow Brain pathology 17 (1), 83-90, 2007 | 216 | 2007 |
| Highly populated turn conformations in natively unfolded tau protein identified from residual dipolar couplings and molecular simulation MD Mukrasch, P Markwick, J Biernat, M von Bergen, P Bernadó, ... Journal of the American Chemical Society 129 (16), 5235-5243, 2007 | 197 | 2007 |
| Structure of tau protein and assembly into paired helical filaments P Friedhoff, M von Bergen, EM Mandelkow, E Mandelkow Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1502 (1), 122-132, 2000 | 193 | 2000 |
| Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study K Weisse, S Winkler, F Hirche, G Herberth, D Hinz, M Bauer, S Röder, ... Allergy 68 (2), 220-228, 2013 | 187 | 2013 |
| MiR-130a, miR-203 and miR-205 jointly repress key oncogenic pathways and are downregulated in prostate carcinoma K Boll, K Reiche, K Kasack, N Mörbt, AK Kretzschmar, JM Tomm, ... Oncogene 32 (3), 277, 2013 | 184 | 2013 |
| Microbiota from the distal guts of lean and obese adolescents exhibit partial functional redundancy besides clear differences in community structure M Ferrer, A Ruiz, F Lanza, SB Haange, A Oberbach, H Till, R Bargiela, ... Environmental microbiology 15 (1), 211-226, 2013 | 173 | 2013 |