| Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ... Nature 491 (7422), 119, 2012 | 3158 | 2012 |
| Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease JC Barrett, S Hansoul, DL Nicolae, JH Cho, RH Duerr, JD Rioux, SR Brant, ... Nature genetics 40 (8), 955, 2008 | 2623 | 2008 |
| Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease JC Barrett, S Hansoul, DL Nicolae, JH Cho, RH Duerr, JD Rioux, SR Brant, ... Nature genetics 40 (8), 955, 2008 | 2623 | 2008 |
| Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci A Franke, DPB McGovern, JC Barrett, K Wang, GL Radford-Smith, ... Nature genetics 42 (12), 1118, 2010 | 2327 | 2010 |
| Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 CA Anderson, G Boucher, CW Lees, A Franke, M D'Amato, KD Taylor, ... Nature genetics 43 (3), 246, 2011 | 1250 | 2011 |
| Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13. 1 and modulates expression of PTGER4 C Libioulle, E Louis, S Hansoul, C Sandor, F Farnir, D Franchimont, ... PLoS genetics 3 (4), e58, 2007 | 567 | 2007 |
| Nursing VHL Search Portal L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ... Nature 491 (7422), 119-24, 2012 | 372 | 2012 |
| Proteolytic processing of interleukin-1 family cytokines: variations on a common theme IS Afonina, C Müller, SJ Martin, R Beyaert Immunity 42 (6), 991-1004, 2015 | 194 | 2015 |
| Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease Y Momozawa, M Mni, K Nakamura, W Coppieters, S Almer, L Amininejad, ... Nature genetics 43 (1), 43, 2011 | 178 | 2011 |
| High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ... Nature genetics 47 (2), 172, 2015 | 162 | 2015 |
| Heterogeneity of the gut microbiome in mice: guidelines for optimizing experimental design D Laukens, BM Brinkman, J Raes, M De Vos, P Vandenabeele FEMS microbiology reviews 40 (1), 117-132, 2015 | 149 | 2015 |
| The paradox of the unfolded protein response in cancer Y Vandewynckel, D Laukens, A Geerts, E Bogaerts, A Paridaens, ... Anticancer research 33 (11), 4683-4694, 2013 | 132 | 2013 |
| CARD15 gene polymorphisms in patients with spondyloarthropathies identify a specific phenotype previously related to Crohn’s disease D Laukens, H Peeters, D Marichal, B Vander Cruyssen, H Mielants, ... Annals of the rheumatic diseases 64 (6), 930-935, 2005 | 90 | 2005 |
| Decreased colonization of fecal Clostridium coccoides/Eubacterium rectale species from ulcerative colitis patients in an in vitro dynamic gut model with mucin … J Vermeiren, P Van den Abbeele, D Laukens, LK Vigsnæs, M De Vos, ... FEMS microbiology ecology 79 (3), 685-696, 2012 | 83 | 2012 |
| Radiological sacroiliitis, a hallmark of spondylitis, is linked with CARD15 gene polymorphisms in patients with Crohn’s disease H Peeters, B Vander Cruyssen, D Laukens, P Coucke, D Marichal, ... Annals of the rheumatic diseases 63 (9), 1131-1134, 2004 | 77 | 2004 |
| Hydroxylase inhibition abrogates TNF-α–induced intestinal epithelial damage by hypoxia-inducible factor-1–dependent repression of FADD P Hindryckx, M De Vos, P Jacques, L Ferdinande, H Peeters, K Olievier, ... The Journal of Immunology 185 (10), 6306-6316, 2010 | 63 | 2010 |
| Butyrate-producing bacteria supplemented in vitro to Crohn’s disease patient microbiota increased butyrate production and enhanced intestinal epithelial barrier integrity A Geirnaert, M Calatayud, C Grootaert, D Laukens, S Devriese, ... Scientific reports 7 (1), 11450, 2017 | 57 | 2017 |
| Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut L Allais, FM Kerckhof, S Verschuere, KR Bracke, R De Smet, D Laukens, ... Environmental microbiology 18 (5), 1352-1363, 2016 | 57 | 2016 |
| Involvement of endoplasmic reticulum stress in inflammatory bowel disease: a different implication for colonic and ileal disease? S Bogaert, M De Vos, K Olievier, H Peeters, D Elewaut, B Lambrecht, ... PloS one 6 (10), e25589, 2011 | 57 | 2011 |
| Role of placental growth factor in mesenteric neoangiogenesis in a mouse model of portal hypertension C Van Steenkiste, A Geerts, E Vanheule, H Van Vlierberghe, F De Vos, ... Gastroenterology 137 (6), 2112-2124. e6, 2009 | 57 | 2009 |