| Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system T Serafini, SA Colamarino, ED Leonardo, H Wang, R Beddington, ... Cell 87 (6), 1001-1014, 1996 | 1254 | 1996 |
| An LDL-receptor-related protein mediates Wnt signalling in mice KI Pinson, J Brennan, S Monkley, BJ Avery, WC Skarnes Nature 407 (6803), 535, 2000 | 1212 | 2000 |
| A conditional knockout resource for the genome-wide study of mouse gene function WC Skarnes, B Rosen, AP West, M Koutsourakis, W Bushell, V Iyer, ... Nature 474 (7351), 337, 2011 | 1061 | 2011 |
| The knockout mouse project CP Austin, JF Battey, A Bradley, M Bucan, M Capecchi, FS Collins, ... Nature genetics 36 (9), 921, 2004 | 609 | 2004 |
| Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes A Gossler, AL Joyner, J Rossant, WC Skarnes Science 244 (4903), 463-465, 1989 | 578 | 1989 |
| Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects B Shen, W Zhang, J Zhang, J Zhou, J Wang, L Chen, L Wang, A Hodgkins, ... Nature methods 11 (4), 399, 2014 | 564 | 2014 |
| Functional analysis of secreted and transmembrane proteins critical to mouse development KJ Mitchell, KI Pinson, OG Kelly, J Brennan, J Zupicich, P Scherz, ... Nature genetics 28 (3), 241, 2001 | 425 | 2001 |
| Defining brain wiring patterns and mechanisms through gene trapping in mice PA Leighton, KJ Mitchell, LV Goodrich, X Lu, K Pinson, P Scherz, ... Nature 410 (6825), 174, 2001 | 408 | 2001 |
| Neuropilin-2 regulates the development of select cranial and sensory nerves and hippocampal mossy fiber projections H Chen, A Bagri, JA Zupicich, Y Zou, E Stoeckli, SJ Pleasure, ... Neuron 25 (1), 43-56, 2000 | 377 | 2000 |
| Capturing genes encoding membrane and secreted proteins important for mouse development WC Skarnes, JE Moss, SM Hurtley, RS Beddington Proceedings of the National Academy of Sciences 92 (14), 6592-6596, 1995 | 369 | 1995 |
| A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice. WC Skarnes, BA Auerbach, AL Joyner Genes & Development 6 (6), 903-918, 1992 | 345 | 1992 |
| High-throughput discovery of novel developmental phenotypes ME Dickinson, AM Flenniken, X Ji, L Teboul, MD Wong, JK White, ... Nature 537 (7621), 508, 2016 | 298 | 2016 |
| Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes JK White, AK Gerdin, NA Karp, E Ryder, M Buljan, JN Bussell, J Salisbury, ... Cell 154 (2), 452-464, 2013 | 297 | 2013 |
| The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice OG Kelly, KI Pinson, WC Skarnes Development 131 (12), 2803-2815, 2004 | 291 | 2004 |
| Agouti C57BL/6N embryonic stem cells for mouse genetic resources SJ Pettitt, Q Liang, XY Rairdan, JL Moran, HM Prosser, DR Beier, ... Nature methods 6 (7), 493, 2009 | 288 | 2009 |
| Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators D Landeira, S Sauer, R Poot, M Dvorkina, L Mazzarella, HF Jørgensen, ... Nature cell biology 12 (6), 618, 2010 | 272 | 2010 |
| Production of a mutation in mouse En-2 gene by homologous recombination in embryonic stem cells AL Joyner, WC Skarnes, J Rossant Nature 338 (6211), 153, 1989 | 262 | 1989 |
| ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a X Gao, P Tate, P Hu, R Tjian, WC Skarnes, Z Wang Proceedings of the National Academy of Sciences 105 (18), 6656-6661, 2008 | 260 | 2008 |
| BayGenomics: a resource of insertional mutations in mouse embryonic stem cells D Stryke, M Kawamoto, CC Huang, SJ Johns, LA King, CA Harper, ... Nucleic acids research 31 (1), 278-281, 2003 | 253 | 2003 |
| The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse P Tate, W Skarnes, A Bird Nature genetics 12 (2), 205, 1996 | 250 | 1996 |
