| Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases B Brueckner, RG Boy, P Siedlecki, T Musch, HC Kliem, P Zielenkiewicz, ... Cancer research 65 (14), 6305-6311, 2005 | 460 | 2005 |
| Discovery of two novel, small-molecule inhibitors of DNA methylation P Siedlecki, RG Boy, T Musch, B Brueckner, S Suhai, F Lyko, ... Journal of medicinal chemistry 49 (2), 678-683, 2006 | 143 | 2006 |
| Mammalian DNA methyltransferases P Siedlecki, P Zielenkiewicz ACTA BIOCHIMICA POLONICA-ENGLISH EDITION- 53 (2), 245, 2006 | 136 | 2006 |
| Establishment and functional validation of a structural homology model for human DNA methyltransferase 1 P Siedlecki, RG Boy, S Comagic, R Schirrmacher, M Wiessler, ... Biochemical and biophysical research communications 306 (2), 558-563, 2003 | 60 | 2003 |
| Performance of machine-learning scoring functions in structure-based virtual screening M Wójcikowski, PJ Ballester, P Siedlecki Scientific reports 7, 46710, 2017 | 56 | 2017 |
| Nicotiana tabacum osmotic stress-activated kinase is regulated by phosphorylation on Ser-154 and Ser-158 in the kinase activation loop AM Burza, I Pękala, J Sikora, P Siedlecki, P Malagocki, M Bucholc, ... Journal of Biological Chemistry 281 (45), 34299-34311, 2006 | 53 | 2006 |
| A specialized histone H1 variant is required for adaptive responses to complex abiotic stress and related DNA methylation in Arabidopsis K Rutowicz, M Puzio, J Halibart-Puzio, M Lirski, M Kotliński, MA Kroteń, ... Plant physiology 169 (3), 2080-2101, 2015 | 49 | 2015 |
| Synthesis and in vitro evaluation of biotinylated RG108: a high affinity compound for studying binding interactions with human DNA methyltransferases E Schirrmacher, C Beck, B Brueckner, F Schmitges, P Siedlecki, ... Bioconjugate chemistry 17 (2), 261-266, 2006 | 43 | 2006 |
| Development and evaluation of a deep learning model for protein–ligand binding affinity prediction MM Stepniewska-Dziubinska, P Zielenkiewicz, P Siedlecki Bioinformatics 34 (21), 3666-3674, 2018 | 32 | 2018 |
| Open Drug Discovery Toolkit (ODDT): a new open-source player in the drug discovery field M Wójcikowski, P Zielenkiewicz, P Siedlecki Journal of cheminformatics 7 (1), 26, 2015 | 26 | 2015 |
| Antimicrobial susceptibility profiling and genotyping of Staphylococcus aureus isolates from bovine mastitis in Poland T Jagielski, E Puacz, A Lisowski, P Siedlecki, W Dudziak, J Międzobrodzki, ... Journal of dairy science 97 (10), 6122-6128, 2014 | 23 | 2014 |
| Sequence diversity and potential recombination events in the coat protein gene of Apple stem pitting virus B Komorowska, P Siedlecki, S Kaczanowski, B Hasiów-Jaroszewska, ... Virus research 158 (1-2), 263-267, 2011 | 22 | 2011 |
| e-LiSe—an online tool for finding needles in the ‘(Medline) haystack’ A Gladki, P Siedlecki, S Kaczanowski, P Zielenkiewicz Bioinformatics 24 (8), 1115-1117, 2008 | 16 | 2008 |
| Rhythmic diel pattern of gene expression in juvenile maize leaf M Jończyk, A Sobkowiak, P Siedlecki, P Biecek, J Trzcinska-Danielewicz, ... PLoS One 6 (8), e23628, 2011 | 11 | 2011 |
| Targeting peroxiredoxin 1 impairs growth of breast cancer cells and potently sensitises these cells to prooxidant agents M Bajor, AO Zych, A Graczyk-Jarzynka, A Muchowicz, M Firczuk, ... British journal of cancer 119 (7), 873, 2018 | 10 | 2018 |
| Genetic diversity of SCN5A gene and its possible association with the concealed form of Brugada syndrome development in Polish group of patients B Uziębło-Życzkowska, G Gielerak, P Siedlecki, B Pająk BioMed research international 2014, 2014 | 7 | 2014 |
| Inhibitors of Dna Methylation in Tumor Cells RG Boy, F Lyko, P Siedlecki US Patent App. 10/591,867, 2008 | 7 | 2008 |
| The High Throughput Sequence Annotation Service (HT-SAS)–the shortcut from sequence to true Medline words S Kaczanowski, P Siedlecki, P Zielenkiewicz BMC bioinformatics 10 (1), 148, 2009 | 6 | 2009 |
| DiSCuS: an open platform for (not only) virtual screening results management M Wójcikowski, P Zielenkiewicz, P Siedlecki Journal of chemical information and modeling 54 (1), 347-354, 2014 | 5 | 2014 |
| Genetic diversity of hemagglutinin gene of A (H1N1) pdm09 influenza strains isolated in Taiwan and its potential impact on HA-neutralizing epitope interaction K Łepek, B Pająk, P Siedlecki, M Niemcewicz, J Kocik, HS Wu, JR Yang, ... Human vaccines & immunotherapeutics 10 (3), 577-585, 2014 | 4 | 2014 |