| Jaks and STATs: biological implications WJ Leonard, JJ O'Shea Annual review of immunology 16 (1), 293-322, 1998 | 1860 | 1998 |
| Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation A Laurence, CM Tato, TS Davidson, Y Kanno, Z Chen, Z Yao, RB Blank, ... Immunity 26 (3), 371-381, 2007 | 1410 | 2007 |
| Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes MF McDermott, I Aksentijevich, J Galon, EM McDermott, BW Ogunkolade, ... Cell 97 (1), 133-144, 1999 | 1239 | 1999 |
| Cytokine signaling in 2002: new surprises in the Jak/Stat pathway JJ O'Shea, M Gadina, RD Schreiber cell 109 (2), S121-S131, 2002 | 1225 | 2002 |
| Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells JJ O’Shea, WE Paul Science 327 (5969), 1098-1102, 2010 | 1207 | 2010 |
| Generation of pathogenic TH17 cells in the absence of TGF-β signalling K Ghoreschi, A Laurence, XP Yang, CM Tato, MJ McGeachy, JE Konkel, ... Nature 467 (7318), 967, 2010 | 1162 | 2010 |
| Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome JD Milner, JM Brenchley, A Laurence, AF Freeman, BJ Hill, KM Elias, ... Nature 452 (7188), 773, 2008 | 1069 | 2008 |
| Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells G Wei, L Wei, J Zhu, C Zang, J Hu-Li, Z Yao, K Cui, Y Kanno, TY Roh, ... Immunity 30 (1), 155-167, 2009 | 990 | 2009 |
| Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system JS Stumhofer, A Laurence, EH Wilson, E Huang, CM Tato, LM Johnson, ... Nature immunology 7 (9), 937, 2006 | 978 | 2006 |
| The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo MJ McGeachy, Y Chen, CM Tato, A Laurence, B Joyce-Shaikh, ... Nature immunology 10 (3), 314, 2009 | 926 | 2009 |
| T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells AA Lighvani, DM Frucht, D Jankovic, H Yamane, J Aliberti, BD Hissong, ... Proceedings of the National Academy of Sciences 98 (26), 15137-15142, 2001 | 859 | 2001 |
| Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development SM Russell, N Tayebi, H Nakajima, MC Riedy, JL Roberts, MJ Aman, ... Science 270 (5237), 797-800, 1995 | 776 | 1995 |
| Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10 JS Stumhofer, JS Silver, A Laurence, PM Porrett, TH Harris, LA Turka, ... Nature immunology 8 (12), 1363, 2007 | 771 | 2007 |
| Janus kinases in immune cell signaling K Ghoreschi, A Laurence, JJ O’Shea Immunological reviews 228 (1), 273-287, 2009 | 734 | 2009 |
| Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice H Mizoguchi, JJ O'Shea, DL Longo, CM Loeffler, DW McVicar, AC Ochoa Science 258 (5089), 1795-1798, 1992 | 721 | 1992 |
| Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID SM Russell, JA Johnston, M Noguchi, M Kawamura, CM Bacon, ... Science 266 (5187), 1042-1045, 1994 | 720 | 1994 |
| Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22 H Takatori, Y Kanno, WT Watford, CM Tato, G Weiss, II Ivanov, DR Littman, ... Journal of Experimental Medicine 206 (1), 35-41, 2009 | 686 | 2009 |
| IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner L Wei, A Laurence, KM Elias, JJ O'Shea Journal of biological chemistry 282 (48), 34605-34610, 2007 | 683 | 2007 |
| Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells Z Chen, A Laurence, Y Kanno, M Pacher-Zavisin, BM Zhu, C Tato, ... Proceedings of the national academy of sciences 103 (21), 8137-8142, 2006 | 677 | 2006 |
| Cytokines and autoimmunity JJ O'Shea, A Ma, P Lipsky Nature Reviews Immunology 2 (1), 37, 2002 | 677 | 2002 |
