Título / AutorAño
mTOR: a pharmacologic target for autophagy regulation
YC Kim, KL Guan
The Journal of clinical investigation 125 (1), 25-32
2015
Metabolic control of autophagy
L Galluzzi, F Pietrocola, B Levine, G Kroemer
Cell 159 (6), 1263-1276
2014
Small molecule inhibition of the autophagy kinase ULK1 and identification of ULK1 substrates
DF Egan, MGH Chun, M Vamos, H Zou, J Rong, CJ Miller, HJ Lou, ...
Molecular cell 59 (2), 285-297
2015
Essential role for autophagy in life span extension
F Madeo, A Zimmermann, MC Maiuri, G Kroemer
The Journal of clinical investigation 125 (1), 85-93
2015
Metabolic control of longevity
C López-Otín, L Galluzzi, JMP Freije, F Madeo, G Kroemer
Cell 166 (4), 802-821
2016
Growing knowledge of the mTOR signaling network
K Huang, DC Fingar
Seminars in cell & developmental biology 36, 79-90
2014
Current treatment strategies for inhibiting mTOR in cancer
F Chiarini, C Evangelisti, JA McCubrey, AM Martelli
Trends in pharmacological sciences 36 (2), 124-135
2015
Cellular senescence: a translational perspective
JL Kirkland, T Tchkonia
EBioMedicine 21, 21-28
2017
mTOR inhibitors in cancer therapy
J Xie, X Wang, CG Proud
F1000Research 5
2016
Amino acid sensing by mTORC1: intracellular transporters mark the spot
DCI Goberdhan, C Wilson, AL Harris
Cell metabolism 23 (4), 580-589
2016
Tuberous sclerosis complex
EP Henske, S Jóźwiak, JC Kingswood, JR Sampson, EA Thiele
Nature reviews Disease primers 2, 16035
2016
Macrophage metabolism controls tumor blood vessel morphogenesis and metastasis
M Wenes, M Shang, M Di Matteo, J Goveia, R Martín-Pérez, J Serneels, ...
Cell metabolism 24 (5), 701-715
2016
Autophagy, lipophagy and lysosomal lipid storage disorders
C Ward, N Martinez-Lopez, EG Otten, B Carroll, D Maetzel, R Singh, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …
2016
Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21
M Cornu, W Oppliger, V Albert, AM Robitaille, F Trapani, L Quagliata, ...
Proceedings of the National Academy of Sciences 111 (32), 11592-11599
2014
Therapeutic targeting of autophagy
CG Towers, A Thorburn
EBioMedicine 14, 15-23
2016
Mutations in TSC1, TSC2, and MTOR are associated with response to rapalogs in patients with metastatic renal cell carcinoma
DJ Kwiatkowski, TK Choueiri, AP Fay, BI Rini, AR Thorner, G De Velasco, ...
Clinical Cancer Research 22 (10), 2445-2452
2016
The expanding role of mTOR in cancer cell growth and proliferation
M Cargnello, J Tcherkezian, PP Roux
Mutagenesis 30 (2), 169-176
2015
Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin
DM Gundermann, DK Walker, PT Reidy, MS Borack, JM Dickinson, ...
American Journal of Physiology-Endocrinology and Metabolism 306 (10), E1198 …
2014
Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
L Ferrucci, E Fabbri
Nature reviews cardiology, 1
2018
Strategies and challenges in clinical trials targeting human aging
JC Newman, S Milman, SK Hashmi, SN Austad, JL Kirkland, JB Halter, ...
Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …
2016
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