Alejandro Schaffer
Alejandro Schaffer
Computer Scientist, National Institutes of Health
Dirección de correo verificada de helix.nih.gov - Página principal
TítuloCitado porAño
Beyond Synthetic Lethality: Charting the Landscape of Pairwise Gene Expression States Associated with Survival in Cancer
A Magen, AD Sahu, JS Lee, M Sharmin, A Lugo, JS Gutkind, AA Schäffer, ...
Cell reports 28 (4), 938-948. e6, 2019
22019
Deconvolution of copy number alterations combining bulk and single-cell genomic data
H Lei, B Lyu, EM Gertz, AA Schaeffer, X Shi, K Wu, G Li, L Xu, Y Hou, ...
Cancer Research 79 (13 Supplement), 1650-1650, 2019
2019
NAA10 polyadenylation signal variants cause syndromic microphthalmia
JJ Johnston, KA Williamson, CM Chou, JC Sapp, M Ansari, HM Chapman, ...
Journal of medical genetics 56 (7), 444-452, 2019
22019
GRAF-pop: A Fast Distance-Based Method To Infer Subject Ancestry from Multiple Genotype Datasets Without Principal Components Analysis
Y Jin, AA Schaffer, M Feolo, JB Holmes, BL Kattman
G3: Genes, Genomes, Genetics, g3. 200925.2018, 2019
2019
Tumor Copy Number Deconvolution Integrating Bulk and Single-Cell Sequencing Data
H Lei, B Lyu, EM Gertz, AA Schaeffer, X Shi, K Wu, G Li, L Xu, Y Hou, ...
International Conference on Research in Computational Molecular Biology, 174-189, 2019
22019
Fibronectin Costimulation of CD40L Expression Integrates Innate and Adaptive Inflammatory Signals
J Ragheb, Y Zhang, N Bushar, H Oh, EM Gertz, A Patnaik, S Chakrabarty, ...
The Journal of Immunology 202 (1 Supplement), 186.10-186.10, 2019
2019
Hypomorphic caspase activation and recruitment domain 11 (CARD11) mutations associated with diverse immunologic phenotypes with or without atopic disease
B Dorjbal, JR Stinson, CA Ma, MA Weinreich, B Miraghazadeh, ...
Journal of Allergy and Clinical Immunology 143 (4), 1482-1495, 2019
17*2019
Beyond synthetic lethality: charting the landscape of clinically relevant genetic interactions in cancer
A Magen, A Das, JS Lee, M Sharmin, A Lugo, JS Gutkind, AA Schäffer, ...
Available at SSRN 3329251, 2019
2019
VADR: validation and annotation of virus sequence submissions to GenBank
AA Schäffer, E Hatcher, L Yankie, L Shonkwiler, JR Brister, ...
bioRxiv, 852657, 2019
2019
Higher prevalence of homologous recombination-deficiency in lung squamous carcinoma from African Americans
S Sinha, KA Mitchell, A Zingone, E Bowman, N Sinha, AA Schäffer, ...
bioRxiv, 651794, 2019
2019
Tumor Copy Number Data Deconvolution Integrating Bulk and Single-cell Sequencing Data
H Lei, B Lyu, EM Gertz, AA Schaffer, R Schwartz
2018 IEEE 8th International Conference on Computational Advances in Bio and …, 2018
2018
Autosomal recessive Noonan syndrome associated with biallelic LZTR1 variants
JJ Johnston, JJ van der Smagt, JA Rosenfeld, AT Pagnamenta, A Alswaid, ...
Genetics in Medicine 20 (10), 1175, 2018
292018
Genome-wide changes in protein translation efficiency are associated with autism
IB Rogozin, EM Gertz, PV Baranov, E Poliakov, AA Schaffer
Genome biology and evolution 10 (8), 1902-1919, 2018
42018
Genomic dynamics in breast cancer progression analyzed by miFISH analysis
IM Torres, L Hernandez, J Tzeng, R Schwartz, A Schaffer, EM Gertz, ...
Cancer Research 78 (13 Supplement), 2189-2189, 2018
2018
ZNF341 controls STAT3 expression and thereby immunocompetence
S Frey-Jakobs, JM Hartberger, M Fliegauf, C Bossen, ML Wehmeyer, ...
Science immunology 3 (24), eaat4941, 2018
192018
The evolution of single cell-derived colorectal cancer cell lines is dominated by the continued selection of tumor-specific genomic imbalances, despite random chromosomal …
D Wangsa, R Braun, M Schiefer, EM Gertz, D Bronder, I Quintanilla, ...
Carcinogenesis 39 (8), 993-1005, 2018
72018
Aneuploidy, TP53 mutation, and amplification of MYC correlate with increased intratumor heterogeneity and poor prognosis of breast cancer patients
J Oltmann, K Heselmeyer‐Haddad, LS Hernandez, R Meyer, I Torres, ...
Genes, Chromosomes and Cancer 57 (4), 165-175, 2018
112018
Plasma cell deficiency in human subjects with heterozygous mutations in Sec61 translocon alpha 1 subunit (SEC61A1)
D Schubert, MC Klein, S Hassdenteufel, A Caballero-Oteyza, L Yang, ...
Journal of Allergy and Clinical Immunology 141 (4), 1427-1438, 2018
82018
Genomic determinants of lymph node metastasis and radioresistance in oral squamous cell carcinoma
PG Bhosale, M Pandey, M Shah, MB Mahimkar, S Cristea, ...
Proceedings of the forty second annual conference of Environmental Mutagen …, 2018
2018
Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies
R Joehanes, X Zhang, T Huan, C Yao, S Ying, QT Nguyen, CY Demirkale, ...
Genome biology 18 (1), 16, 2017
732017
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