| Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... Nature 500 (7463), 415, 2013 | 4511 | 2013 |
| Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia XS Puente, M Pinyol, V Quesada, L Conde, GR Ordóñez, N Villamor, ... Nature 475 (7354), 101, 2011 | 1363 | 2011 |
| Human and mouse proteases: a comparative genomic approach XS Puente, LM Sánchez, CM Overall, C López-Otín Nature Reviews Genetics 4 (7), 544, 2003 | 974 | 2003 |
| Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia V Quesada, L Conde, N Villamor, GR Ordóñez, P Jares, L Bassaganyas, ... Nature genetics 44 (1), 47, 2012 | 869 | 2012 |
| The genome of a songbird WC Warren, DF Clayton, H Ellegren, AP Arnold, LDW Hillier, A Künstner, ... Nature 464 (7289), 757, 2010 | 696 | 2010 |
| Genome analysis of the platypus reveals unique signatures of evolution WC Warren, LDW Hillier, JAM Graves, E Birney, CP Ponting, F Grützner, ... Nature 453 (7192), 175, 2008 | 664 | 2008 |
| Comparative and demographic analysis of orang-utan genomes DP Locke, LDW Hillier, WC Warren, KC Worley, LV Nazareth, DM Muzny, ... Nature 469 (7331), 529, 2011 | 494 | 2011 |
| Non-coding recurrent mutations in chronic lymphocytic leukaemia XS Puente, S Beà, R Valdés-Mas, N Villamor, J Gutiérrez-Abril, ... Nature 526 (7574), 519, 2015 | 460 | 2015 |
| Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia M Kulis, S Heath, M Bibikova, AC Queirós, A Navarro, G Clot, ... Nature genetics 44 (11), 1236, 2012 | 413 | 2012 |
| Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma XS Puente, AM Pendás, E Llano, G Velasco, C López-Otín Cancer Research 56 (5), 944-949, 1996 | 406 | 1996 |
| Landscape of somatic mutations and clonal evolution in mantle cell lymphoma S Beà, R Valdés-Mas, A Navarro, I Salaverria, D Martín-Garcia, P Jares, ... Proceedings of the National Academy of Sciences 110 (45), 18250-18255, 2013 | 315 | 2013 |
| Identification and characterization of a novel human matrix metalloproteinase with unique structural characteristics, chromosomal location, and tissue distribution AM Pendás, V Knäuper, XS Puente, E Llano, MG Mattei, S Apte, ... Journal of Biological Chemistry 272 (7), 4281-4286, 1997 | 268 | 1997 |
| Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8) A Gutiérrez-Fernández, M Inada, M Balbín, A Fueyo, AS Pitiot, A Astudillo, ... The FASEB Journal 21 (10), 2580-2591, 2007 | 235 | 2007 |
| Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-α convertase activity but does not activate pro-MMP2 WR English, XS Puente, JMP Freije, V Knäuper, A Amour, ... Journal of Biological Chemistry 275 (19), 14046-14055, 2000 | 233 | 2000 |
| Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy G Mariño, JA Urı́a, XS Puente, V Quesada, J Bordallo, C López-Otı́n Journal of Biological Chemistry 278 (6), 3671-3678, 2003 | 227 | 2003 |
| POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia AJ Ramsay, V Quesada, M Foronda, L Conde, A Martínez-Trillos, ... Nature genetics 45 (5), 526, 2013 | 211 | 2013 |
| Matrix metalloproteinases and tumor progression JMP Freije, M Balbín, AM Pendás, LM Sánchez, XS Puente, C López-Otín New Trends in Cancer for the 21st Century, 91-107, 2003 | 211 | 2003 |
| LPS responsiveness and neutrophil chemotaxis in vivo require PMN MMP-8 activity AM Tester, JH Cox, AR Connor, AE Starr, RA Dean, XS Puente, ... PloS one 2 (3), e312, 2007 | 210 | 2007 |
| A genomic analysis of rat proteases and protease inhibitors XS Puente, C López-Otín Genome research 14 (4), 609-622, 2004 | 205 | 2004 |
| Polymorphisms in XPC, XPD, XRCC1, and XRCC3 DNA repair genes and lung cancer risk in a population of northern Spain MF López-Cima, P González-Arriaga, L García-Castro, T Pascual, ... BMC cancer 7 (1), 162, 2007 | 188 | 2007 |