| Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome … SS Lee, T Pineau, J Drago, EJ Lee, JW Owens, DL Kroetz, ... Molecular and cellular biology 15 (6), 3012-3022, 1995 | 1744 | 1995 |
| Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor P Fernandez-Salguero, T Pineau, DM Hilbert, T McPhail, SS Lee, ... Science 268 (5211), 722-726, 1995 | 1105 | 1995 |
| The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. S Kimura, Y Hara, T Pineau, P Fernandez-Salguero, CH Fox, JM Ward, ... Genes & development 10 (1), 60-69, 1996 | 1090 | 1996 |
| Aryl-hydrocarbon receptor-deficient mice are resistant to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced toxicity PM Fernandez-Salguero, DM Hilbert, S Rudikoff, JM Ward, FJ Gonzalez Toxicology and applied pharmacology 140 (1), 173-179, 1996 | 863 | 1996 |
| Role of CYP2E1 in the hepatotoxicity of acetaminophen SST Lee, JTM Buters, T Pineau, P Fernandez-Salguero, FJ Gonzalez Journal of Biological Chemistry 271 (20), 12063-12067, 1996 | 636 | 1996 |
| Genomic instability in Gadd45a-deficient mice MC Hollander, MS Sheikh, DV Bulavin, K Lundgren, L Augeri-Henmueller, ... Nature genetics 23 (2), 176, 1999 | 513 | 1999 |
| Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity. X Wei, HL McLeod, J McMurrough, FJ Gonzalez, P Fernandez-Salguero The Journal of clinical investigation 98 (3), 610-615, 1996 | 421 | 1996 |
| The aryl hydrocarbon receptor: studies using the AHR-null mice FJ Gonzalez, P Fernandez-Salguero Drug Metabolism and Disposition 26 (12), 1194-1198, 1998 | 397 | 1998 |
| The aryl hydrocarbon receptor, more than a xenobiotic‐interacting protein R Barouki, X Coumoul, PM Fernandez-Salguero FEBS letters 581 (19), 3608-3615, 2007 | 383 | 2007 |
| Lesions of aryl-hydrocarbon receptor–deficient mice PM Fernandez-Salguero, JM Ward, JP Sundberg, FJ Gonzalez Veterinary pathology 34 (6), 605-614, 1997 | 357 | 1997 |
| A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A gnes and identification of variant CYP2A6 alleles P Fernandez-Salguero, SMG Hoffman, S Cholerton, H Mohrenweiser, ... American journal of human genetics 57 (3), 651, 1995 | 341 | 1995 |
| Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development LM Esteban, C Vicario-Abejón, P Fernández-Salguero, ... Molecular and cellular biology 21 (5), 1444-1452, 2001 | 335 | 2001 |
| Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy H Furuya, P Fernandez-Salguero, W Gregory, H Taber, A Steward, ... Pharmacogenetics and Genomics 5 (6), 389-392, 1995 | 319 | 1995 |
| Resveratrol‐induced apoptosis in MCF‐7 human breast cancer cells involves a caspase‐independent mechanism with downregulation of Bcl‐2 and NF‐κB E Pozo‐Guisado, JM Merino, S Mulero‐Navarro, MJ Lorenzo‐Benayas, ... International journal of cancer 115 (1), 74-84, 2005 | 256 | 2005 |
| The antiproliferative activity of resveratrol results in apoptosis in MCF-7 but not in MDA-MB-231 human breast cancer cells: cell-specific alteration of the cell cycle E Pozo-Guisado, A Alvarez-Barrientos, S Mulero-Navarro, ... Biochemical pharmacology 64 (9), 1375-1386, 2002 | 245 | 2002 |
| Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice. JM Peters, MG Narotsky, G Elizondo, PM Fernandez-Salguero, ... Toxicological sciences: an official journal of the Society of Toxicology 47 …, 1999 | 242 | 1999 |
| Targeted disruption of the microsomal epoxide hydrolase gene microsomal epoxide hydrolase is required for the carcinogenic activity of 7, 12-dimethylbenz [a] anthracene M Miyata, G Kudo, YH Lee, TJ Yang, HV Gelboin, P Fernandez-Salguero, ... Journal of Biological Chemistry 274 (34), 23963-23968, 1999 | 209 | 1999 |
| Altered cell cycle control at the G2/M phases in aryl hydrocarbon receptor-null embryo fibroblast G Elizondo, P Fernandez-Salguero, MS Sheikh, GY Kim, AJ Fornace, ... Molecular pharmacology 57 (5), 1056-1063, 2000 | 204 | 2000 |
| Aryl-hydrocarbon receptor is an inhibitory regulator of lipid synthesis and of commitment to adipogenesis DL Alexander, LG Ganem, P Fernandez-Salguero, F Gonzalez, ... Journal of cell science 111 (22), 3311-3322, 1998 | 191 | 1998 |
| Mechanisms Involved in Resveratrol‐Induced Apoptosis and Cell Cycle Arrest in Prostate Cancer—Derived Cell Lines DA Benitez, E Pozo‐Guisado, A Alvarez‐Barrientos, ... Journal of andrology 28 (2), 282-293, 2007 | 188 | 2007 |