Pedro M. Fernandez-Salguero
Pedro M. Fernandez-Salguero
Professor of Biochemistry and Molecular Biology, University of Extremadura
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TítuloCitado porAño
Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome …
SS Lee, T Pineau, J Drago, EJ Lee, JW Owens, DL Kroetz, ...
Molecular and cellular biology 15 (6), 3012-3022, 1995
17441995
Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor
P Fernandez-Salguero, T Pineau, DM Hilbert, T McPhail, SS Lee, ...
Science 268 (5211), 722-726, 1995
11051995
The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary.
S Kimura, Y Hara, T Pineau, P Fernandez-Salguero, CH Fox, JM Ward, ...
Genes & development 10 (1), 60-69, 1996
10901996
Aryl-hydrocarbon receptor-deficient mice are resistant to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced toxicity
PM Fernandez-Salguero, DM Hilbert, S Rudikoff, JM Ward, FJ Gonzalez
Toxicology and applied pharmacology 140 (1), 173-179, 1996
8631996
Role of CYP2E1 in the hepatotoxicity of acetaminophen
SST Lee, JTM Buters, T Pineau, P Fernandez-Salguero, FJ Gonzalez
Journal of Biological Chemistry 271 (20), 12063-12067, 1996
6361996
Genomic instability in Gadd45a-deficient mice
MC Hollander, MS Sheikh, DV Bulavin, K Lundgren, L Augeri-Henmueller, ...
Nature genetics 23 (2), 176, 1999
5131999
Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity.
X Wei, HL McLeod, J McMurrough, FJ Gonzalez, P Fernandez-Salguero
The Journal of clinical investigation 98 (3), 610-615, 1996
4211996
The aryl hydrocarbon receptor: studies using the AHR-null mice
FJ Gonzalez, P Fernandez-Salguero
Drug Metabolism and Disposition 26 (12), 1194-1198, 1998
3971998
The aryl hydrocarbon receptor, more than a xenobiotic‐interacting protein
R Barouki, X Coumoul, PM Fernandez-Salguero
FEBS letters 581 (19), 3608-3615, 2007
3832007
Lesions of aryl-hydrocarbon receptor–deficient mice
PM Fernandez-Salguero, JM Ward, JP Sundberg, FJ Gonzalez
Veterinary pathology 34 (6), 605-614, 1997
3571997
A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A gnes and identification of variant CYP2A6 alleles
P Fernandez-Salguero, SMG Hoffman, S Cholerton, H Mohrenweiser, ...
American journal of human genetics 57 (3), 651, 1995
3411995
Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development
LM Esteban, C Vicario-Abejón, P Fernández-Salguero, ...
Molecular and cellular biology 21 (5), 1444-1452, 2001
3352001
Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy
H Furuya, P Fernandez-Salguero, W Gregory, H Taber, A Steward, ...
Pharmacogenetics and Genomics 5 (6), 389-392, 1995
3191995
Resveratrol‐induced apoptosis in MCF‐7 human breast cancer cells involves a caspase‐independent mechanism with downregulation of Bcl‐2 and NF‐κB
E Pozo‐Guisado, JM Merino, S Mulero‐Navarro, MJ Lorenzo‐Benayas, ...
International journal of cancer 115 (1), 74-84, 2005
2562005
The antiproliferative activity of resveratrol results in apoptosis in MCF-7 but not in MDA-MB-231 human breast cancer cells: cell-specific alteration of the cell cycle
E Pozo-Guisado, A Alvarez-Barrientos, S Mulero-Navarro, ...
Biochemical pharmacology 64 (9), 1375-1386, 2002
2452002
Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice.
JM Peters, MG Narotsky, G Elizondo, PM Fernandez-Salguero, ...
Toxicological sciences: an official journal of the Society of Toxicology 47 …, 1999
2421999
Targeted disruption of the microsomal epoxide hydrolase gene microsomal epoxide hydrolase is required for the carcinogenic activity of 7, 12-dimethylbenz [a] anthracene
M Miyata, G Kudo, YH Lee, TJ Yang, HV Gelboin, P Fernandez-Salguero, ...
Journal of Biological Chemistry 274 (34), 23963-23968, 1999
2091999
Altered cell cycle control at the G2/M phases in aryl hydrocarbon receptor-null embryo fibroblast
G Elizondo, P Fernandez-Salguero, MS Sheikh, GY Kim, AJ Fornace, ...
Molecular pharmacology 57 (5), 1056-1063, 2000
2042000
Aryl-hydrocarbon receptor is an inhibitory regulator of lipid synthesis and of commitment to adipogenesis
DL Alexander, LG Ganem, P Fernandez-Salguero, F Gonzalez, ...
Journal of cell science 111 (22), 3311-3322, 1998
1911998
Mechanisms Involved in Resveratrol‐Induced Apoptosis and Cell Cycle Arrest in Prostate Cancer—Derived Cell Lines
DA Benitez, E Pozo‐Guisado, A Alvarez‐Barrientos, ...
Journal of andrology 28 (2), 282-293, 2007
1882007
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Artículos 1–20