Randall J. Kimple, M.D. Ph.D.
TítuloCitado porAño
G-protein signaling: back to the future
CR McCudden, MD Hains, RJ Kimple, DP Siderovski, FS Willard
Cellular and molecular life sciences 62 (5), 551-577, 2005
5192005
Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos
K Colombo, SW Grill, RJ Kimple, FS Willard, DP Siderovski, P Gönczy
Science 300 (5627), 1957-1961, 2003
2752003
Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits
RJ Kimple, ME Kimple, L Betts, J Sondek, DP Siderovski
Nature 416 (6883), 878, 2002
2652002
RGS12 and RGS14 GoLoco Motifs Are GαiInteraction Sites with Guanine Nucleotide Dissociation Inhibitor Activity
RJ Kimple, L De Vries, H Tronchère, CI Behe, RA Morris, MG Farquhar, ...
Journal of Biological Chemistry 276 (31), 29275-29281, 2001
2462001
Enhanced radiation sensitivity in HPV-positive head and neck cancer
RJ Kimple, MA Smith, GC Blitzer, AD Torres, JA Martin, RZ Yang, CR Peet, ...
Cancer research 73 (15), 4791-4800, 2013
2362013
Return of the GDI: the GoLoco motif in cell division
FS Willard, RJ Kimple, DP Siderovski
Annual review of biochemistry 73 (1), 925-951, 2004
1922004
Association of p16INK4a overexpression with improved outcomes in young patients with squamous cell cancers of the oral tongue
SL Harris, LB Thorne, WT Seaman, D Neil Hayes, ME Couch, RJ Kimple
Head & neck 33 (11), 1622-1627, 2011
1352011
Melanoma cells show a heterogeneous range of sensitivity to ionizing radiation and are radiosensitized by inhibition of B-RAF with PLX-4032
MJ Sambade, EC Peters, NE Thomas, WK Kaufmann, RJ Kimple, ...
Radiotherapy and Oncology 98 (3), 394-399, 2011
1192011
AXL mediates resistance to cetuximab therapy
TM Brand, M Iida, AP Stein, KL Corrigan, CM Braverman, N Luthar, ...
Cancer research 74 (18), 5152-5164, 2014
1092014
Structure-based protocol for identifying mutations that enhance protein–protein binding affinities
DW Sammond, ZM Eletr, C Purbeck, RJ Kimple, DP Siderovski, ...
Journal of molecular biology 371 (5), 1392-1404, 2007
972007
Never‐smokers, never‐drinkers: unique clinical subgroup of young patients with head and neck squamous cell cancers
SL Harris, RJ Kimple, DN Hayes, ME Couch, JG Rosenman
Head & Neck: Journal for the Sciences and Specialties of the Head and Neck …, 2010
902010
Review of the clinical and biologic aspects of human papillomavirus-positive squamous cell carcinomas of the head and neck
GC Blitzer, MA Smith, SL Harris, RJ Kimple
International Journal of Radiation Oncology* Biology* Physics 88 (4), 761-770, 2014
892014
RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote
L Martin-McCaffrey, FS Willard, AJ Oliveira-dos-Santos, DRC Natale, ...
Developmental cell 7 (5), 763-769, 2004
702004
Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif
RJ Kimple, FS Willard, MD Hains, MB Jones, GK Nweke, DP Siderovski
Biochemical Journal 378 (3), 801-808, 2004
692004
Prevalence of human papillomavirus in oropharyngeal squamous cell carcinoma in the United States across time
AP Stein, S Saha, M Yu, RJ Kimple, PF Lambert
Chemical research in toxicology 27 (4), 462-469, 2014
682014
Development and characterization of HPV-positive and HPV-negative head and neck squamous cell carcinoma tumorgrafts
RJ Kimple, PM Harari, AD Torres, RZ Yang, BJ Soriano, M Yu, ...
Clinical Cancer Research 19 (4), 855-864, 2013
652013
Prevalence of human papillomavirus in oropharyngeal cancer: a systematic review
AP Stein, S Saha, JL Kraninger, AD Swick, M Yu, PF Lambertg, R Kimple
Cancer journal (Sudbury, Mass.) 21 (3), 138, 2015
622015
D2 dopamine receptor activation of potassium channels is selectively decoupled by Gαi‐specific GoLoco motif peptides
CK Webb, CR McCudden, FS Willard, RJ Kimple, DP Siderovski, ...
Journal of neurochemistry 92 (6), 1408-1418, 2005
602005
Human papillomavirus type 16 E7 oncoprotein causes a delay in repair of DNA damage
JW Park, KP Nickel, AD Torres, D Lee, PF Lambert, RJ Kimple
Radiotherapy and Oncology 113 (3), 337-344, 2014
582014
AXL is a logical molecular target in head and neck squamous cell carcinoma
TM Brand, M Iida, AP Stein, KL Corrigan, CM Braverman, JP Coan, ...
Clinical cancer research 21 (11), 2601-2612, 2015
532015
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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