| Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli BA Pfeifer, SJ Admiraal, H Gramajo, DE Cane, C Khosla Science 291 (5509), 1790-1792, 2001 | 717 | 2001 |
| Transcriptional regulation of the redD transcriptional activator gene accounts for growth‐phase‐dependent production of the antibiotic undecylprodigiosin in Streptomyces … E Takano, HC Gramajo, E Strauch, N Andres, J White, MJ Bibb Molecular microbiology 6 (19), 2797-2804, 1992 | 219 | 1992 |
| Stationary‐phase production of the antibiotic actinorhodin in Streptomyces coelicolor A3(2) is transcriptionally regulated HC Gramajo, E Takano, MJ Bibb Molecular microbiology 7 (6), 837-845, 1993 | 217 | 1993 |
| Production of the potent antibacterial polyketide erythromycin C in Escherichia coli S Peirú, HG Menzella, E Rodriguez, J Carney, H Gramajo Appl. Environ. Microbiol. 71 (5), 2539-2547, 2005 | 132 | 2005 |
| Structure-based inhibitor design of AccD5, an essential acyl-CoA carboxylase carboxyltransferase domain of Mycobacterium tuberculosis TW Lin, MM Melgar, D Kurth, SJ Swamidass, J Purdon, T Tseng, G Gago, ... Proceedings of the National Academy of Sciences 103 (9), 3072-3077, 2006 | 113 | 2006 |
| Multiple pathways for triacylglycerol biosynthesis in Streptomyces coelicolor A Arabolaza, E Rodriguez, S Altabe, H Alvarez, H Gramajo Appl. Environ. Microbiol. 74 (9), 2573-2582, 2008 | 107 | 2008 |
| Fatty acid biosynthesis in actinomycetes G Gago, L Diacovich, A Arabolaza, SC Tsai, H Gramajo FEMS microbiology reviews 35 (3), 475-497, 2011 | 105 | 2011 |
| Purification and characterization of the acyl carrier protein of the Streptomyces glaucescens tetracenomycin C polyketide synthase. B Shen, RG Summers, H Gramajo, MJ Bibb, CR Hutchinson Journal of bacteriology 174 (11), 3818-3821, 1992 | 105 | 1992 |
| Genetic and biochemical characterization of the α and β components of a propionyl-CoA carboxylase complex of Streptomyces coelicolor A3 (2) E Rodrıguez, H Gramajo Microbiology 145 (11), 3109-3119, 1999 | 99 | 1999 |
| Proteomic studies of diauxic lag in the differentiating prokaryote Streptomyces coelicolor reveal a regulatory network of stress‐induced proteins and central … J Novotna, J Vohradsky, P Berndt, H Gramajo, H Langen, XM Li, W Minas, ... Molecular microbiology 48 (5), 1289-1303, 2003 | 90 | 2003 |
| Kinetic and structural analysis of a new group of acyl-CoA carboxylases found in Streptomyces coelicolor A3 (2) L Diacovich, S Peirú, D Kurth, E Rodrı́guez, F Podestá, C Khosla, ... Journal of Biological Chemistry 277 (34), 31228-31236, 2002 | 79 | 2002 |
| Biochemical and structural characterization of an essential acyl coenzyme A carboxylase from Mycobacterium tuberculosis G Gago, D Kurth, L Diacovich, SC Tsai, H Gramajo Journal of bacteriology 188 (2), 477-486, 2006 | 78 | 2006 |
| Crystal Structure of the β-Subunit of Acyl-CoA Carboxylase: Structure-Based Engineering of Substrate Specificity, L Diacovich, DL Mitchell, H Pham, G Gago, MM Melgar, C Khosla, ... Biochemistry 43 (44), 14027-14036, 2004 | 73 | 2004 |
| The biosynthetic genes for disorazoles, potent cytotoxic compounds that disrupt microtubule formation R Carvalho, R Reid, N Viswanathan, H Gramajo, B Julien Gene 359, 91-98, 2005 | 72 | 2005 |
| Role of an essential acyl coenzyme A carboxylase in the primary and secondary metabolism of Streptomyces coelicolor A3 (2) E Rodrıguez, C Banchio, L Diacovich, MJ Bibb, H Gramajo Appl. Environ. Microbiol. 67 (9), 4166-4176, 2001 | 70 | 2001 |
| Overproduction and localization of components of the polyketide synthase of Streptomyces glaucescens involved in the production of the antibiotic tetracenomycin C. HC Gramajo, J White, CR Hutchinson, MJ Bibb Journal of bacteriology 173 (20), 6475-6483, 1991 | 64 | 1991 |
| ACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteria DG Kurth, GM Gago, A de la Iglesia, BB Lyonnet, TW Lin, HR Morbidoni, ... Microbiology 155 (Pt 8), 2664, 2009 | 53 | 2009 |
| High recovery of prochymosin from inclusion bodies using controlled air oxidation HG Menzella, HC Gramajo, EA Ceccarelli Protein expression and purification 25 (2), 248-255, 2002 | 42 | 2002 |
| redD and actII-ORF4, pathway-specific regulatory genes for antibiotic production in Streptomyces coelicolor A3 (2), are transcribed in vitro by an RNA polymerase holoenzyme … T Fujii, HC Gramajo, E Takano, MJ Bibb Journal of bacteriology 178 (11), 3402-3405, 1996 | 42 | 1996 |
| Transcriptional regulation of lipid homeostasis in mycobacteria V Salzman, S Mondino, C Sala, ST Cole, G Gago, H Gramajo Molecular microbiology 78 (1), 64-77, 2010 | 40 | 2010 |
