| MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 V La Rosa, G Poce, JO Canseco, S Buroni, MR Pasca, M Biava, RM Raju, ... Antimicrobial agents and chemotherapy 56 (1), 324-331, 2012 | 165 | 2012 |
| Synthesis, biological evaluation, and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis: part 2. Synthesis of rigid pyrazolones D Castagnolo, F Manetti, M Radi, B Bechi, M Pagano, A De Logu, ... Bioorganic & medicinal chemistry 17 (15), 5716-5721, 2009 | 147 | 2009 |
| Paclitaxel and docetaxel resistance: molecular mechanisms and development of new generation taxanes E Galletti, M Magnani, ML Renzulli, M Botta ChemMedChem: Chemistry Enabling Drug Discovery 2 (7), 920-942, 2007 | 142 | 2007 |
| Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure− activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors S Pasquini, C Mugnaini, C Tintori, M Botta, A Trejos, RK Arvela, M Larhed, ... Journal of medicinal chemistry 51 (16), 5125-5129, 2008 | 136 | 2008 |
| Synthesis, Biological Evaluation, and Pharmacophore Generation of New Pyridazinone Derivatives with Affinity toward α1- and α2-Adrenoceptors R Barbaro, L Betti, M Botta, F Corelli, G Giannaccini, L Maccari, F Manetti, ... Journal of Medicinal Chemistry 44 (13), 2118-2132, 2001 | 133 | 2001 |
| A unified and quantitative receptor model for the microtubule binding of paclitaxel and epothilone M Wang, X Xia, Y Kim, D Hwang, JM Jansen, M Botta, DC Liotta, ... Organic letters 1 (1), 43-46, 1999 | 127 | 1999 |
| Synthesis, biological evaluation and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis D Castagnolo, A De Logu, M Radi, B Bechi, F Manetti, M Magnani, ... Bioorganic & medicinal chemistry 16 (18), 8587-8591, 2008 | 126 | 2008 |
| Crystal structure of the OXA-48 β-lactamase reveals mechanistic diversity among class D carbapenemases JD Docquier, V Calderone, F De Luca, M Benvenuti, F Giuliani, L Bellucci, ... Chemistry & biology 16 (5), 540-547, 2009 | 124 | 2009 |
| Synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity via palladium-catalyzed heteroannulation of chiral arylpropargylic alcohols M Botta, V Summa, F Corelli, G Di Pietro, P Lombardi Tetrahedron: Asymmetry 7 (5), 1263-1266, 1996 | 118 | 1996 |
| Involvement of polyamine oxidase in wound healing R Angelini, A Tisi, G Rea, MM Chen, M Botta, R Federico, A Cona Plant Physiology 146 (1), 162-177, 2008 | 110 | 2008 |
| Antimycobacterial agents. Novel diarylpyrrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity M Biava, GC Porretta, G Poce, S Supino, D Deidda, R Pompei, P Molicotti, ... Journal of medicinal chemistry 49 (16), 4946-4952, 2006 | 109 | 2006 |
| ATP-competitive inhibitors of mTOR: an update S Schenone, C Brullo, F Musumeci, M Radi, M Botta Current medicinal chemistry 18 (20), 2995-3014, 2011 | 106 | 2011 |
| Antiangiogenic agents: an update on small molecule VEGFR inhibitors S Schenone, F Bondavalli, M Botta Current medicinal chemistry 14 (23), 2495-2516, 2007 | 103 | 2007 |
| Gli1/DNA interaction is a druggable target for Hedgehog‐dependent tumors P Infante, M Mori, R Alfonsi, F Ghirga, F Aiello, S Toscano, C Ingallina, ... The EMBO journal 34 (2), 200-217, 2015 | 100 | 2015 |
| Fibroblast growth factors and their inhibitors F Manetti, F Corelli, M Botta Current pharmaceutical design 6 (18), 1897-1924, 2000 | 98 | 2000 |
| New pyrazolo [3, 4-d] pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation S Schenone, O Bruno, A Ranise, F Bondavalli, C Brullo, P Fossa, L Mosti, ... Bioorganic & medicinal chemistry letters 14 (10), 2511-2517, 2004 | 96 | 2004 |
| Pyrazolo [3, 4-d] pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation F Carraro, A Naldini, A Pucci, GA Locatelli, G Maga, S Schenone, O Bruno, ... Journal of medicinal chemistry 49 (5), 1549-1561, 2006 | 94 | 2006 |
| Antifungal Agents. 10. New Derivatives of 1-[(Aryl)[4-aryl-1H-pyrrol-3-yl]methyl]-1H-imidazole, Synthesis, Anti-Candida Activity, and Quantitative Structure … A Tafi, R Costi, M Botta, R Di Santo, F Corelli, S Massa, A Ciacci, ... Journal of medicinal chemistry 45 (13), 2720-2732, 2002 | 92 | 2002 |
| Computational comparison of microtubule-stabilising agents laulimalide and peloruside with taxol and colchicine O Pineda, J Farràs, L Maccari, F Manetti, M Botta, J Vilarrasa Bioorganic & medicinal chemistry letters 14 (19), 4825-4829, 2004 | 89 | 2004 |
| Synthesis and biological evaluation of new taxoids derived from 2-deacetoxytaxinine J M Botta, S Armaroli, D Castagnolo, G Fontana, P Pera, E Bombardelli Bioorganic & medicinal chemistry letters 17 (6), 1579-1583, 2007 | 86 | 2007 |
