| Rational design of cationic lipids for siRNA delivery SC Semple, A Akinc, J Chen, AP Sandhu, BL Mui, CK Cho, DWY Sah, ... Nature biotechnology 28 (2), 172-176, 2010 | 1312 | 2010 |
| A combinatorial library of lipid-like materials for delivery of RNAi therapeutics A Akinc, A Zumbuehl, M Goldberg, ES Leshchiner, V Busini, N Hossain, ... Nature biotechnology 26 (5), 561-569, 2008 | 1143 | 2008 |
| Lipid-like materials for low-dose, in vivo gene silencing KT Love, KP Mahon, CG Levins, KA Whitehead, W Querbes, JR Dorkin, ... Proceedings of the National Academy of Sciences 107 (5), 1864-1869, 2010 | 814 | 2010 |
| Safety and efficacy of RNAi therapy for transthyretin amyloidosis T Coelho, D Adams, A Silva, P Lozeron, PN Hawkins, T Mant, J Perez, ... New England Journal of Medicine 369 (9), 819-829, 2013 | 799 | 2013 |
| Viral load drives disease in humans experimentally infected with respiratory syncytial virus JP DeVincenzo, T Wilkinson, A Vaishnaw, J Cehelsky, R Meyers, ... American journal of respiratory and critical care medicine 182 (10), 1305-1314, 2010 | 295 | 2010 |
| Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV) J DeVincenzo, JE Cehelsky, R Alvarez, S Elbashir, J Harborth, ... Antiviral research 77 (3), 225-231, 2008 | 288 | 2008 |
| Human Metapneumovirus: lessons learned over the first decade V Schildgen, B van den Hoogen, R Fouchier, RA Tripp, R Alvarez, ... Clinical microbiology reviews 24 (4), 734-754, 2011 | 190 | 2011 |
| Diagnostic approach for differentiating infected from vaccinated poultry on the basis of antibodies to NS1, the nonstructural protein of influenza A virus TM Tumpey, R Alvarez, DE Swayne, DL Suarez Journal of clinical microbiology 43 (2), 676-683, 2005 | 179 | 2005 |
| Respiratory syncytial virus G protein and G protein CX3C motif adversely affect CX3CR1+ T cell responses J Harcourt, R Alvarez, LP Jones, C Henderson, LJ Anderson, RA Tripp The Journal of Immunology 176 (3), 1600-1608, 2006 | 168 | 2006 |
| RNA interference-mediated silencing of the respiratory syncytial virus nucleocapsid defines a potent antiviral strategy R Alvarez, S Elbashir, T Borland, I Toudjarska, P Hadwiger, M John, ... Antimicrobial agents and chemotherapy 53 (9), 3952-3962, 2009 | 159 | 2009 |
| Human metapneumovirus persists in BALB/c mice despite the presence of neutralizing antibodies R Alvarez, KS Harrod, WJ Shieh, S Zaki, RA Tripp Journal of virology 78 (24), 14003-14011, 2004 | 139 | 2004 |
| The immune response to human metapneumovirus is associated with aberrant immunity and impaired virus clearance in BALB/c mice R Alvarez, RA Tripp Journal of virology 79 (10), 5971-5978, 2005 | 108 | 2005 |
| Cytokines and respiratory syncytial virus infection RA Tripp, C Oshansky, R Alvarez Proceedings of the American Thoracic Society 2 (2), 147-149, 2005 | 107 | 2005 |
| Genomic sequences of low-virulence avian paramyxovirus-1 (Newcastle disease virus) isolates obtained from live-bird markets in North America not related to commonly utilized … BS Seal, MG Wise, JC Pedersen, DA Senne, R Alvarez, MS Scott, DJ King, ... Veterinary microbiology 106 (1-2), 7-16, 2005 | 106 | 2005 |
| Arthritis severity and spirochete burden are determined by serotype in the Borrelia turicatae-mouse model of Lyme disease PM Pennington, CD Allred, CS West, R Alvarez, AG Barbour Infection and immunity 65 (1), 285-292, 1997 | 87 | 1997 |
| Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis JS Butler, A Chan, S Costelha, S Fishman, JLS Willoughby, TD Borland, ... Amyloid 23 (2), 109-118, 2016 | 79 | 2016 |
| Bioconjugated nanoparticle detection of respiratory syncytial virus infection RA Tripp, R Alvarez, B Anderson, L Jones, C Weeks, W Chen International journal of nanomedicine 2 (1), 117, 2007 | 77 | 2007 |
| CSF transthyretin neuroprotection in a mouse model of brain ischemia SD Santos, KL Lambertsen, BH Clausen, A Akinc, R Alvarez, B Finsen, ... Journal of neurochemistry 115 (6), 1434-1444, 2010 | 72 | 2010 |
| Monoclonal antibodies to SARS-associated coronavirus (SARS-CoV): identification of neutralizing and antibodies reactive to S, N, M and E viral proteins RA Tripp, LM Haynes, D Moore, B Anderson, A Tamin, BH Harcourt, ... Journal of virological methods 128 (1-2), 21-28, 2005 | 71 | 2005 |
| RNA-dependent RNA polymerase gene analysis of worldwide Newcastle disease virus isolates representing different virulence types and their phylogenetic relationship with other … MG Wise, HS Sellers, R Alvarez, BS Seal Virus research 104 (1), 71-80, 2004 | 68 | 2004 |
