| Guidelines for the use and interpretation of assays for monitoring autophagy (3rd Edition) Autophagy 12 (1), 1-222, 0 | 5863* | |
| Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes DJ Klionsky, H Abeliovich, P Agostinis, DK Agrawal, G Aliev, DS Askew, ... Autophagy 4 (2), 151-175, 2008 | 2351 | 2008 |
| Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease C Janus, J Pearson, JA McLaurin, PM Mathews, Y Jiang, SD Schmidt, ... Nature 408 (6815), 979, 2000 | 1777 | 2000 |
| Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study RA Nixon, J Wegiel, A Kumar, WH Yu, C Peterhoff, A Cataldo, AM Cuervo Journal of Neuropathology & Experimental Neurology 64 (2), 113-122, 2005 | 1124 | 2005 |
| The role of autophagy in neurodegenerative disease RA Nixon Nature medicine 19 (8), 983, 2013 | 1117 | 2013 |
| Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease WH Yu, AM Cuervo, A Kumar, CM Peterhoff, SD Schmidt, JH Lee, ... J Cell Biol 171 (1), 87-98, 2005 | 862 | 2005 |
| Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease B Boland, A Kumar, S Lee, FM Platt, J Wegiel, WH Yu, RA Nixon Journal of Neuroscience 28 (27), 6926-6937, 2008 | 822 | 2008 |
| Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations JH Lee, WH Yu, A Kumar, S Lee, PS Mohan, CM Peterhoff, DM Wolfe, ... Cell 141 (7), 1146-1158, 2010 | 806 | 2010 |
| Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration K Saito, JS Elce, JE Hamos, RA Nixon Proceedings of the National Academy of Sciences 90 (7), 2628-2632, 1993 | 640 | 1993 |
| Autophagy, amyloidogenesis and Alzheimer disease RA Nixon Journal of cell science 120 (23), 4081-4091, 2007 | 617 | 2007 |
| Endocytic pathway abnormalities precede amyloid β deposition in sporadic Alzheimer’s disease and Down syndrome: differential effects of APOE genotype and presenilin mutations AM Cataldo, CM Peterhoff, JC Troncoso, T Gomez-Isla, BT Hyman, ... The American journal of pathology 157 (1), 277-286, 2000 | 600 | 2000 |
| Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration A Salehi, JD Delcroix, PV Belichenko, K Zhan, C Wu, JS Valletta, ... Neuron 51 (1), 29-42, 2006 | 464 | 2006 |
| Autophagy and its possible roles in nervous system diseases, damage and repair DC Rubinsztein, M DiFiglia, N Heintz, RA Nixon, ZH Qin, B Ravikumar, ... Autophagy 1 (1), 11-22, 2005 | 439 | 2005 |
| Cdk5 is a key factor in tau aggregation and tangle formation in vivo DK Noble W, Olm V, Takata K, Casey E, Mary O, Meyerson J, Gaynor K ... Neuron 38 (4), 555-65, 2003 | 439* | 2003 |
| Enzymatically active lysosomal proteases are associated with amyloid deposits in Alzheimer brain. AM Cataldo, RA Nixon Proceedings of the National Academy of Sciences 87 (10), 3861-3865, 1990 | 437 | 1990 |
| Autophagy failure in Alzheimer's disease—locating the primary defect RA Nixon, DS Yang Neurobiology of disease 43 (1), 38-45, 2011 | 407 | 2011 |
| Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer’s disease: neuropathologic evidence for a mechanism of increased β-amyloidogenesis AM Cataldo, JL Barnett, C Pieroni, RA Nixon Journal of Neuroscience 17 (16), 6142-6151, 1997 | 405 | 1997 |
| The proteolytic fragments of the Alzheimer’s disease-associated presenilin-1 form heterodimers and occur as a 100–150-kDa molecular mass complex A Capell, J Grünberg, B Pesold, A Diehlmann, M Citron, R Nixon, ... Journal of Biological Chemistry 273 (6), 3205-3211, 1998 | 402 | 1998 |
| Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders F Abdi, JF Quinn, J Jankovic, M McIntosh, JB Leverenz, E Peskind, ... Journal of Alzheimer's Disease 9 (3), 293-348, 2006 | 387 | 2006 |
| Autophagy in neurodegenerative disease: friend, foe or turncoat? RA Nixon Trends in neurosciences 29 (9), 528-535, 2006 | 361 | 2006 |
