| Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase JA Mitchell, P Akarasereenont, C Thiemermann, RJ Flower, JR Vane Proceedings of the National Academy of Sciences 90 (24), 11693-11697, 1993 | 1898 | 1993 |
| Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis TD Warner, F Giuliano, I Vojnovic, A Bukasa, JA Mitchell, JR Vane Proceedings of the National Academy of Sciences 96 (13), 7563-7568, 1999 | 1680 | 1999 |
| Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation JR Vane, JA Mitchell, I Appleton, A Tomlinson, D Bishop-Bailey, J Croxtall, ... Proceedings of the National Academy of Sciences 91 (6), 2046-2050, 1994 | 1197 | 1994 |
| Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells JS Pollock, U Förstermann, JA Mitchell, TD Warner, HH Schmidt, ... Proceedings of the National Academy of Sciences 88 (23), 10480-10484, 1991 | 1092 | 1991 |
| Isoforms of nitric oxide synthase characterization and purification from different cell types U Förstermann, HHHW Schmidt, JS Pollock, H Sheng, JA Mitchell, ... Biochemical pharmacology 42 (10), 1849-1857, 1991 | 1035 | 1991 |
| Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic TD Warner, JA Mitchell The FASEB journal 18 (7), 790-804, 2004 | 810 | 2004 |
| The safety and side effects of monoclonal antibodies TT Hansel, H Kropshofer, T Singer, JA Mitchell, AJT George Nature reviews Drug discovery 9 (4), 325-338, 2010 | 633 | 2010 |
| Nitric oxide‐mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock C Szabo, JA Mitchell, C Thiemermann, JR Vane British journal of pharmacology 108 (3), 786-792, 1993 | 470 | 1993 |
| Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide C Thiemermann, C Szabo, JA Mitchell, JR Vane Proceedings of the National Academy of Sciences 90 (1), 267-271, 1993 | 437 | 1993 |
| Cyclooxygenase-2: regulation and relevance in inflammation JA Mitchell, S Larkin, TJ Williams Biochemical pharmacology 50 (10), 1535-1542, 1995 | 431 | 1995 |
| Reactive oxygen species in acute lung injury F Chabot, JA Mitchell, JM Gutteridge, TW Evans European Respiratory Journal 11 (3), 745-757, 1998 | 402 | 1998 |
| Co‐induction of nitric oxide synthase and cyclo‐oxygenase: interactions between nitric oxide and prostanoids TA Swierkosz, JA Mitchell, TD Warner, RM Botting, JR Vane British journal of pharmacology 114 (7), 1335-1342, 1995 | 392 | 1995 |
| Cyclo‐oxygenase‐2: pharmacology, physiology, biochemistry and relevance to NSAID therapy JA Mitchell, TD Warner British journal of pharmacology 128 (6), 1121-1132, 1999 | 382 | 1999 |
| Endothelin-1 and endothelin-3 release EDRF from isolated perfused arterial vessels of the rat and rabbit. TD Warner, JA Mitchell, JR Vane Journal of cardiovascular pharmacology 13, S85-8; discussion S102, 1989 | 367 | 1989 |
| Induction of cyclo‐oxygenase‐2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone JA Mitchell, MG Belvisi, P Akarasereenont, RA Robbins, OJ Kwon, ... British journal of pharmacology 113 (3), 1008-1014, 1994 | 351 | 1994 |
| Cyclooxygenase-3 (COX-3): filling in the gaps toward a COX continuum? TD Warner, JA Mitchell Proceedings of the National Academy of Sciences 99 (21), 13371-13373, 2002 | 347 | 2002 |
| Phosphorylation by calcium calmodulin-dependent protein kinase II and protein kinase C modulates the activity of nitric oxide synthase M Nakane, J Mitchell, U Förstermann, F Murad Biochemical and biophysical research communications 180 (3), 1396-1402, 1991 | 303 | 1991 |
| The pathogenesis of lung injury following pulmonary resection S Jordan, JA Mitchell, GJ Quinlan, P Goldstraw, TW Evans European Respiratory Journal 15 (4), 790-799, 2000 | 277 | 2000 |
| Redox imbalance in the critically ill JMC Gutteridge, J Mitchell British Medical Bulletin 55 (1), 49-75, 1999 | 268 | 1999 |
| COX isoforms in the cardiovascular system: understanding the activities of non-steroidal anti-inflammatory drugs JA Mitchell, TD Warner Nature reviews Drug discovery 5 (1), 75, 2006 | 263 | 2006 |
Nicholas KirkbyResearch Fellow, Imperial College LondonVerified email at imperial.ac.uk
