Janet M Thornton
Janet M Thornton
Senior Scientist, European Molecular Biology Laboratory - European Institute of Bioinformatics (EMBL-EBI)
Verified email at ebi.ac.uk - Homepage
TitleCited byYear
Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1
DE Martin-Herranz, E Aref-Eshghi, MJ Bonder, TM Stubbs, S Choufani, ...
Genome biology 20 (1), 146, 2019
52019
Identifying pseudoenzymes using functional annotation. How loss of function correlates with mutations in the catalytic site
AJM Ribeiro, JD Tyzack, N Borkakoti, JM Thornton
The FEBS journal, 2019
2019
The Wiles of Creation: Philosophy, Fiction and the ‘Aja’ib Tradition
M Hughes-Warrington, Abelard of Bath, C Burnett, Abhinavagupta, ...
History as Wonder: Beginning with Historiography 71 (1), 189-191, 2019
2019
VarSite: disease variants and protein structure
RA Laskowski, JD Stephenson, I Sillitoe, CA Orengo, JM Thornton
Protein Science, 2019
2019
Deconvoluting the Dementia phenotype using functional computational approaches
D Ivanov, M Hill, N Allen, JM Thornton, J Williams, V Escott-Price
EUROPEAN JOURNAL OF HUMAN GENETICS 27, 1699-1700, 2019
2019
Enrichment and Clustering of Rare Genetic Variants using Shared Protein Structure Domains
JD Stephenson, RA Laskowski, JM Thornton, ME Hurles
EUROPEAN JOURNAL OF HUMAN GENETICS 27, 1717-1717, 2019
2019
Exploring Chemical Biosynthetic Design Space with Transform-MinER
JD Tyzack, AJM Ribeiro, N Borkakoti, JM Thornton
ACS synthetic biology, 2019
2019
Emerging concepts in pseudoenzyme classification, evolution, and signaling
AJM Ribeiro, S Das, N Dawson, R Zaru, S Orchard, JM Thornton, ...
Science signaling 12 (594), eaat9797, 2019
42019
VarMap: a web tool for mapping genomic coordinates to protein sequence and structure and retrieving protein structural annotations
JD Stephenson, RA Laskowski, A Nightingale, ME Hurles, JM Thornton
Bioinformatics, 2019
32019
The widespread increase in inter-individual variability of gene expression in the human brain with age
VR Kedlian, HM Donertas, JM Thornton
Aging (Albany NY) 11 (8), 2253, 2019
22019
Radial piston machine having braking means secured against twisting
L Masson, J Offenburger, S Hirschberg, P Fischer
US Patent 10,221,831, 2019
602019
Finding enzyme cofactors in Protein Data Bank
A Mukhopadhyay, N Borkakoti, L Pravda, JD Tyzack, JM Thornton, ...
Bioinformatics, 2019
22019
Using the drug-protein interactome to identify anti-ageing compounds for humans
M Fuentealba, HM Dönertaş, R Williams, J Labbadia, JM Thornton, ...
PLoS computational biology 15 (1), e1006639, 2019
62019
Gene expression heterogeneity during brain development and aging: temporal changes and functional consequences
M Somel, JM Thornton, HM Dönertaş
bioRxiv, 595249, 2019
2019
PDBe-KB: a community-driven resource for structural and functional annotations
M Varadi, J Berrisford, M Deshpande, SS Nair, A Gutmanas, D Armstrong, ...
Nucleic Acids Research, 2019
22019
Structural analysis of pathogenic missense mutations in GABRA2 and identification of a novel de novo variant in the desensitization gate
A Sanchis-Juan, MA Hasenahuer, JA Baker, A McTague, K Barwick, ...
bioRxiv, 678219, 2019
2019
Meta-Analysis of the Gene Expression Profiles of Aging Brain Reveals Consistent Increase in Heterogeneity
U Isildak, M Somel, J Thornton, HM Donertas
BioRxiv, 595249, 2019
2019
The variability of expression of many genes and most functional pathways is observed to increase with age in brain transcriptome data
VR Kedlian, HM Donertas, JM Thornton
BioRxiv, 526491, 2019
2019
Exploring Enzyme Evolution from Changes in Sequence, Structure, and Function
JD Tyzack, N Furnham, I Sillitoe, CM Orengo, JM Thornton
Computational Methods in Protein Evolution, 263-275, 2019
22019
Identifying potential ageing-modulating drugs in silico
HM Dönertaş, M Fuentealba, L Partridge, JM Thornton
Trends in Endocrinology & Metabolism, 2018
12018
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