Lewis Cantley - Google Scholar Citations

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Co-authors

Ji LuoNational Cancer InstituteVerified email at nih.gov
Costas LyssiotisAssistant Professor of Physiology, University of MichiganVerified email at lyssiotis.com
David FrumanProfessor of Molecular Biology & Biochemistry, UC IrvineVerified email at uci.edu
Alex TokerVerified email at bidmc.harvard.edu
Jason LocasaleDuke UniversityVerified email at duke.edu
C. Ronald KahnJoslin Diabetes Center and Harvard Medical SchoolVerified email at joslin.harvard.edu
David R. KaplanHospital for Sick ChildrenVerified email at sickkids.ca
John BlenisProfessor of Pharmacology, Weill Cornell MedicineVerified email at med.cornell.edu
Steven ShoelsonHarvard Medical SchoolVerified email at joslin.harvard.edu
Reuben ShawThe Salk Institute of Biological StudiesVerified email at salk.edu
Kurt AugerGlaxoSmithKlineVerified email at gsk.com
Ronald A. DePinhoMD AndersonVerified email at mdanderson.org
Malcolm WhitmanHarvardVerified email at hms.harvard.edu
Pier Paolo PandolfiDirector, Cancer Center and Cancer Research Institute, Beth Israel Deaconess Medical CenterVerified email at bidmc.harvard.edu
Gerburg WulfAssociate Professor in Medicine, Harvard Medical SchoolVerified email at bidmc.harvard.edu
Atsuo T. SasakiUniversity of Cincinnati, College of MedicineVerified email at uc.edu
Heather ChristofkAssociate Professor of Molecular and Medical Pharmacology and Biological Chemistry, UCLAVerified email at mednet.ucla.edu
Benjamin G. NeelProfessor of Medicine, NYU School of Medicine; Director, Laura and Isaac Perlmutter Cancer CenterVerified email at nyulangone.org
Bin ZhengMassachusetts General Hospital, Harvard Medical SchoolVerified email at cbrc2.mgh.harvard.edu
Thomas FrankeMount Sinai School of MedicineVerified email at mssm.edu

Lewis Cantley

Weill Cornell Medical College

Verified email at med.cornell.edu

cancer metabolism signal transduction PI 3-Kinase Protein kinases


Title	Cited by	Year
Understanding the Warburg effect: the metabolic requirements of cell proliferation MG Vander Heiden, LC Cantley, CB Thompson science 324 (5930), 1029-1033, 2009	9090	2009
The phosphoinositide 3-kinase pathway LC Cantley Science 296 (5573), 1655-1657, 2002	5911	2002
AKT/PKB signaling: navigating downstream BD Manning, LC Cantley Cell 129 (7), 1261-1274, 2007	5399	2007
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling JA Engelman, K Zejnullahu, T Mitsudomi, Y Song, C Hyland, JO Park, ... science 316 (5827), 1039-1043, 2007	4320	2007
SH2 domains recognize specific phosphopeptide sequences S Zhou, SE Shoelson, M Chaudhuri, G Gish, T Pawson, WG Haser, F King, ... Cell 72 (5), 767-778, 1993	3043	1993
Oncogenes and signal transduction LC Cantley, KR Auger, C Carpenter, B Duckworth, A Graziani, R Kapeller, ... Cell 64 (2), 281-302, 1991	2989	1991
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate L Dang, DW White, S Gross, BD Bennett, MA Bittinger, EM Driggers, ... Nature 462 (7274), 739, 2009	2800	2009
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism JA Engelman, J Luo, LC Cantley Nature Reviews Genetics 7 (8), 606, 2006	2767	2006
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway LC Cantley, BG Neel Proceedings of the National Academy of Sciences 96 (8), 4240-4245, 1999	2432	1999
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth HR Christofk, MG Vander Heiden, MH Harris, A Ramanathan, ... Nature 452 (7184), 230, 2008	2282	2008
Ras, PI (3) K and mTOR signalling controls tumour cell growth RJ Shaw, LC Cantley Nature 441 (7092), 424, 2006	2117	2006
PI3K: downstream AKTion blocks apoptosis TF Franke, DR Kaplan, LC Cantley Cell 88 (4), 435-437, 1997	1902	1997
Phosphoinositide kinases DA Fruman, RE Meyers, LC Cantley Annual review of biochemistry 67 (1), 481-507, 1998	1807	1998
PI3K pathway alterations in cancer: variations on a theme TL Yuan, LC Cantley Oncogene 27 (41), 5497, 2008	1787	2008
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin RJ Shaw, KA Lamia, D Vasquez, SH Koo, N Bardeesy, RA DePinho, ... Science 310 (5754), 1642-1646, 2005	1785	2005
Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs JC Obenauer, LC Cantley, MB Yaffe Nucleic acids research 31 (13), 3635-3641, 2003	1701	2003
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3, 4-bisphosphate TF Franke, DR Kaplan, LC Cantley, A Toker Science 275 (5300), 665-668, 1997	1683	1997
The structural basis for 14-3-3: phosphopeptide binding specificity MB Yaffe, K Rittinger, S Volinia, PR Caron, A Aitken, H Leffers, ... Cell 91 (7), 961-971, 1997	1630	1997
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress RJ Shaw, M Kosmatka, N Bardeesy, RL Hurley, LA Witters, RA DePinho, ... Proceedings of the National Academy of Sciences 101 (10), 3329-3335, 2004	1599	2004
Recognition of unique carboxyl-terminal motifs by distinct PDZ domains Z Songyang, AS Fanning, C Fu, J Xu, SM Marfatia, AH Chishti, ... Science 275 (5296), 73-77, 1997	1542	1997

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