Thomas Look
Thomas Look
Professor of Pediatrics, Harvard Medical School
Verified email at dfci.harvard.edu - Homepage
TitleCited byYear
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
AP Weng, AA Ferrando, W Lee, JP Morris, LB Silverman, ...
Science 306 (5694), 269-271, 2004
26282004
Acute lymphoblastic leukemia
CH Pui
Encyclopedia of Cancer, 23-26, 2011
25952011
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
SW Morris, MN Kirstein, MB Valentine, KG Dittmer, DN Shapiro, ...
Science 263 (5151), 1281-1284, 1994
21811994
Acute lymphoblastic leukaemia
CH Pui, LL Robison, AT Look
The Lancet 371 (9617), 1030-1043, 2008
16202008
The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1
CJ Sherr, CW Rettenmier, R Sacca, MF Roussel, AT Look, ER Stanley
Cell 41 (3), 665-676, 1985
16201985
Oncogenic transcription factors in the human acute leukemias
AT Look
Science 278 (5340), 1059-1064, 1997
13631997
A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish
P Niethammer, C Grabher, AT Look, TJ Mitchison
Nature 459 (7249), 996, 2009
11302009
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
AA Ferrando, DS Neuberg, J Staunton, ML Loh, C Huard, SC Raimondi, ...
Cancer cell 1 (1), 75-87, 2002
10732002
Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
T Teitz, T Wei, MB Valentine, EF Vanin, J Grenet, VA Valentine, FG Behm, ...
Nature medicine 6 (5), 529, 2000
8862000
Activating mutations in ALK provide a therapeutic target in neuroblastoma
RE George, T Sanda, M Hanna, S Fröhling, W Luther II, J Zhang, Y Ahn, ...
Nature 455 (7215), 975, 2008
7712008
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
T Palomero, WK Lim, DT Odom, ML Sulis, PJ Real, A Margolin, ...
Proceedings of the National Academy of Sciences 103 (48), 18261-18266, 2006
7572006
Hematology of infancy and childhood
DG Nathan, FA Oski
WB Saunders Co., Philadelphia, PA, 1987
7141987
Identification of breakpoints in t (8; 21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt
P Erickson, J Gao, KS Chang, T Look, E Whisenant, S Raimondi, ...
Blood 80 (7), 1825-1831, 1992
6681992
Human aminopeptidase N is a receptor for human coronavirus 229E
CL Yeager, RA Ashmun, RK Williams, CB Cardellichio, LH Shapiro, ...
Nature 357 (6377), 420, 1992
6501992
Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study.
AT Look, FA Hayes, JJ Shuster, EC Douglass, RP Castleberry, ...
Journal of Clinical Oncology 9 (4), 581-591, 1991
6451991
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors
J O'Neil, J Grim, P Strack, S Rao, D Tibbitts, C Winter, J Hardwick, ...
Journal of Experimental Medicine 204 (8), 1813-1824, 2007
5962007
Cellular DNA content as a predictor of response to chemotherapy in infants with unresectable neuroblastoma
AT Look, FA Hayes, R Nitschke, NB McWilliams, AA Green
New England Journal of Medicine 311 (4), 231-235, 1984
5541984
Obinutuzumab as frontline treatment of chronic lymphocytic leukemia: updated results of the CLL11 study
V Goede, K Fischer, A Engelke, R Schlag, S Lepretre, LFC Montero, ...
Leukemia 29 (7), 1602, 2015
553*2015
BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma
EE Patton, HR Widlund, JL Kutok, KR Kopani, JF Amatruda, RD Murphey, ...
Current Biology 15 (3), 249-254, 2005
5522005
Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N.
AT Look, RA Ashmun, LH Shapiro, SC Peiper
The Journal of clinical investigation 83 (4), 1299-1307, 1989
5331989
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Articles 1–20