Jennifer Wortman
Jennifer Wortman
Vice President, Clinical Discovery and Research Technologies, Seres Therapeutics
Verified email at serestherapeutics.com
TitleCited byYear
Characteristics of the microbiome form and function of complete responders to Anti-PD1 and healthy individuals implicate donor selection for clinical trial design
MAW Khan, J Wargo, B Helmink, E Burton, C Spencer, J McQuade, ...
JOURNAL FOR IMMUNOTHERAPY OF CANCER 7, 2019
2019
Designed bacterial compositions
J Button, D Cook, H Matthew, MJL McKenzie, K Litcofsky, A Martinez, ...
US Patent App. 15/778,095, 2019
2019
623–Ser-287, an Investigational Microbiome Therapeutic, Induces Widespread Transcriptional Changes Related to Clinical Remission in a Placebo-Controlled, Double-Blind …
L Diao, MC Nnamani, E OBrien, C Desjardins, A Martinez, S Simmons, ...
Gastroenterology 156 (6), S-130, 2019
12019
Stool donor qualification and collection from metastatic melanoma (MM) patients (pts) who have responded to checkpoint inhibitors (CPI) for manufacturing of fecal microbiota …
EM Burton, IC Glitza, J Mahoney, J Wortman, J Aunis, K Litcofsky, D Cook, ...
Journal of Clinical Oncology 37 (8_suppl), TPS146-TPS146, 2019
2019
Abstract B063: Leveraging gut microbiota networks to impact tumor immunotherapy
L Jayaraman, J Sceneay, S Srinivasan, K Halley, M Bist, K Cieciuch, ...
Cancer Immunology Research 7 (2 Supplement), B063-B063, 2019
2019
621. Treatment of Recurrent Clostridium difficile Infection with SER-109 Increases the Concentration of Secondary Bile Acids in a Dose-Dependent Manner
M Henn, C Ford, E O’Brien, J Wortman, L Diao, C Desjardins, ...
Open Forum Infectious Diseases 5 (suppl_1), S226-S227, 2018
32018
1641. Treatment of Recurrent Clostridium difficile Infection With SER-109 Reduces Gastrointestinal Carriage of Antimicrobial Resistance Genes
C Ford, M Henn, J Bryant, L Diao, J Wortman, A Tomlinson, K Litcofsky, ...
Open Forum Infectious Diseases 5 (suppl_1), S46-S47, 2018
2018
RNA-Seq Profile Reveals Th-1 and Th-17-Type of Immune Responses in Mice Infected Systemically with Aspergillus fumigatus
J Shankar, GC Cerqueira, JR Wortman, KV Clemons, DA Stevens
Mycopathologia 183 (4), 645-658, 2018
62018
Abstract LB-283: Leveraging gut microbiota networks to impact tumor immunotherapy
J Sceneay, S Srinivasan, K Halley, G Marnellos, J Wortman, M Henn, ...
Cancer Research 78 (13 Supplement), LB-283-LB-283, 2018
2018
Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus
RP de Vries, R Riley, A Wiebenga, G Aguilar-Osorio, S Amillis, ...
Genome biology 18 (1), 28, 2017
1432017
Revitalization of a forward genetic screen identifies three new regulators of fungal secondary metabolism in the genus Aspergillus
BT Pfannenstiel, X Zhao, J Wortman, P Wiemann, K Throckmorton, ...
MBio 8 (5), e01246-17, 2017
182017
Gastrointestinal Tract Microbiome Dynamics Following Treatment with SER-109, an Investigational Oral Microbiome Therapeutic to Reduce the Recurrence of Clostridium difficile …
M Henn, C Ford, E O’Brien, J Wortman, S Simmons, L Diao, K Litcofsky, ...
Open forum infectious diseases 4 (suppl_1), S389-S390, 2017
22017
Corrigendum: Mobile genes in the human microbiome are structured from global to individual scales
IL Brito, S Yilmaz, K Huang, L Xu, SD Jupiter, AP Jenkins, W Naisilisili, ...
Nature 544 (7648), 124, 2017
22017
Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks
GC Cerqueira, AM Earl, CM Ernst, YH Grad, JP Dekker, M Feldgarden, ...
Proceedings of the National Academy of Sciences 114 (5), 1135-1140, 2017
632017
Revitalization of a forward genetic screen identifies three new regulators of fungal secondary metabolism in the genus Aspergillus. mBio. 2017
BT Pfannenstiel, X Zhao, J Wortman, P Wiemann, K Throckmorton, ...
September 5 (8), 5, 2017
32017
Corrigendum: Mobile genes in the human microbiome are structured from global to individual scales (Nature (2016) 535 (435-439
IL Brito, S Yilmaz, K Huang, L Xu, SD Jupiter, AP Jenkins, W Naisilisili, ...
Nature Publishing Group, 2017
2017
Discovery of McrA, a master regulator of Aspergillus secondary metabolism
CE Oakley, M Ahuja, WW Sun, R Entwistle, T Akashi, J Yaegashi, CJ Guo, ...
Molecular microbiology 103 (2), 347-365, 2017
262017
Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome
EP Hamilton, A Kapusta, PE Huvos, SL Bidwell, N Zafar, H Tang, ...
Elife 5, e19090, 2016
472016
Mobile genes in the human microbiome are structured from global to individual scales
IL Brito, S Yilmaz, K Huang, L Xu, SD Jupiter, AP Jenkins, W Naisilisili, ...
Nature 535 (7612), 435, 2016
882016
Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance
CA Desjardins, KA Cohen, V Munsamy, T Abeel, K Maharaj, BJ Walker, ...
Nature genetics 48 (5), 544, 2016
892016
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