| Executive summary: heart disease and stroke statistics—2015 update: a report from the American Heart Association D Mozaffarian, EJ Benjamin, AS Go, DK Arnett, MJ Blaha, M Cushman, ... Circulation 131 (4), 434-441, 2015 | 26021* | 2015 |
| Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease … TA Pearson, GA Mensah, RW Alexander, JL Anderson, RO Cannon III, ... circulation 107 (3), 499-511, 2003 | 6898 | 2003 |
| Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. KK Griendling, CA Minieri, JD Ollerenshaw, RW Alexander Circulation research 74 (6), 1141-1148, 1994 | 3013 | 1994 |
| Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries PL Ludmer, AP Selwyn, TL Shook, RR Wayne, GH Mudge, RW Alexander, ... New England Journal of Medicine 315 (17), 1046-1051, 1986 | 2946 | 1986 |
| The heart: arteries and veins JW Hurst, RB Logue, RC Schlant, NK Wenger McGraw-Hill, 1978 | 1607* | 1978 |
| Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease CB Treasure, JL Klein, WS Weintraub, JD Talley, ME Stillabower, ... New England Journal of Medicine 332 (8), 481-487, 1995 | 1584 | 1995 |
| Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor TJ Murphy, RW Alexander, KK Griendling, MS Runge, KE Bernstein Nature 351 (6323), 233, 1991 | 1369 | 1991 |
| Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. N Marui, MK Offermann, R Swerlick, C Kunsch, CA Rosen, M Ahmad, ... The Journal of clinical investigation 92 (4), 1866-1874, 1993 | 1158 | 1993 |
| Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase. K Nishida, DG Harrison, JP Navas, AA Fisher, SP Dockery, M Uematsu, ... The Journal of clinical investigation 90 (5), 2092-2096, 1992 | 814 | 1992 |
| Elevation of C-reactive protein in “active” coronary artery disease BC Berk, WS Weintraub, RW Alexander The American journal of cardiology 65 (3), 168-172, 1990 | 801 | 1990 |
| p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II Role in vascular smooth muscle cell hypertrophy M Ushio-Fukai, RW Alexander, M Akers, KK Griendling Journal of Biological Chemistry 273 (24), 15022-15029, 1998 | 700 | 1998 |
| Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase GW De Keulenaer, DC Chappell, N Ishizaka, RM Nerem, RW Alexander, ... Circulation research 82 (10), 1094-1101, 1998 | 680 | 1998 |
| Dilation of normal and constriction of atherosclerotic coronary arteries caused by the cold pressor test. EG Nabel, P Ganz, JB Gordon, RW Alexander, AP Selwyn Circulation 77 (1), 43-52, 1988 | 661 | 1988 |
| Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework D Cook, D Brown, R Alexander, R March, P Morgan, G Satterthwaite, ... Nature reviews Drug discovery 13 (6), 419-431, 2014 | 654 | 2014 |
| Regulation of endothelial cell nitric oxide synthase mRNA expression by shear stress M Uematsu, Y Ohara, JP Navas, K Nishida, TJ Murphy, RW Alexander, ... American Journal of Physiology-Cell Physiology 269 (6), C1371-C1378, 1995 | 646 | 1995 |
| Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells M Ushio-Fukai, RW Alexander, M Akers, QQ Yin, Y Fujio, K Walsh, ... Journal of Biological Chemistry 274 (32), 22699-22704, 1999 | 637 | 1999 |
| A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II) AM Ross, RJ Gibbons, GW Stone, RA Kloner, RW Alexander, ... Journal of the American College of Cardiology 45 (11), 1775-1780, 2005 | 628 | 2005 |
| Oscillatory shear stress stimulates adhesion molecule expression in cultured human endothelium DC Chappell, SE Varner, RM Nerem, RM Medford, RW Alexander Circulation research 82 (5), 532-539, 1998 | 626 | 1998 |
| Hypertension and the pathogenesis of atherosclerosis: oxidative stress and the mediation of arterial inflammatory response: a new perspective RW Alexander Hypertension 25 (2), 155-161, 1995 | 621 | 1995 |
| Nitric oxide regulates vascular cell adhesion molecule 1 gene expression and redox-sensitive transcriptional events in human vascular endothelial cells BV Khan, DG Harrison, MT Olbrych, RW Alexander, RM Medford Proceedings of the National Academy of Sciences 93 (17), 9114-9119, 1996 | 590 | 1996 |
Michael GimbroneProfessor of Pathology, Harvard Medical SchoolVerified email at partners.org
