| Systematic identification of genomic markers of drug sensitivity in cancer cells MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ... Nature 483 (7391), 570, 2012 | 1641 | 2012 |
| Prospective derivation of a living organoid biobank of colorectal cancer patients M van de Wetering, HE Francies, JM Francis, G Bounova, F Iorio, A Pronk, ... Cell 161 (4), 933-945, 2015 | 710 | 2015 |
| A landscape of pharmacogenomic interactions in cancer F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ... Cell 166 (3), 740-754, 2016 | 513 | 2016 |
| Structural and functional analysis of cellular networks with CellNetAnalyzer S Klamt, J Saez-Rodriguez, ED Gilles BMC systems biology 1 (1), 2, 2007 | 509 | 2007 |
| Critical assessment of automated flow cytometry data analysis techniques N Aghaeepour, G Finak, H Hoos, TR Mosmann, R Brinkman, R Gottardo, ... Nature methods 10 (3), 228, 2013 | 424 | 2013 |
| A methodology for the structural and functional analysis of signaling and regulatory networks S Klamt, J Saez-Rodriguez, JA Lindquist, L Simeoni, ED Gilles BMC bioinformatics 7 (1), 56, 2006 | 400 | 2006 |
| Towards a rigorous assessment of systems biology models: the DREAM3 challenges RJ Prill, D Marbach, J Saez-Rodriguez, PK Sorger, LG Alexopoulos, ... PloS one 5 (2), e9202, 2010 | 389 | 2010 |
| A community effort to assess and improve drug sensitivity prediction algorithms JC Costello, LM Heiser, E Georgii, M Gönen, MP Menden, NJ Wang, ... Nature biotechnology 32 (12), 1202, 2014 | 356 | 2014 |
| Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction J Saez‐Rodriguez, LG Alexopoulos, J Epperlein, R Samaga, ... Molecular systems biology 5 (1), 2009 | 318 | 2009 |
| A logical model provides insights into T cell receptor signaling J Saez-Rodriguez, L Simeoni, JA Lindquist, R Hemenway, U Bommhardt, ... PLoS computational biology 3 (8), e163, 2007 | 312 | 2007 |
| Logic-based models for the analysis of cell signaling networks MK Morris, J Saez-Rodriguez, PK Sorger, DA Lauffenburger Biochemistry 49 (15), 3216-3224, 2010 | 283 | 2010 |
| Evaluation of methods for modeling transcription factor sequence specificity MT Weirauch, A Cote, R Norel, M Annala, Y Zhao, TR Riley, ... Nature biotechnology 31 (2), 126, 2013 | 266 | 2013 |
| Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties MP Menden, F Iorio, M Garnett, U McDermott, CH Benes, PJ Ballester, ... PLoS one 8 (4), e61318, 2013 | 217 | 2013 |
| Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling DM Wittmann, J Krumsiek, J Saez-Rodriguez, DA Lauffenburger, S Klamt, ... BMC systems biology 3 (1), 98, 2009 | 199 | 2009 |
| The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput data R Samaga, J Saez-Rodriguez, LG Alexopoulos, PK Sorger, S Klamt PLoS computational biology 5 (8), e1000438, 2009 | 194 | 2009 |
| Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH da Costa, ... Nature 537 (7621), 544, 2016 | 193 | 2016 |
| A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ... Cell reports 17 (4), 1193-1205, 2016 | 186 | 2016 |
| Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling BB Aldridge, J Saez-Rodriguez, JL Muhlich, PK Sorger, DA Lauffenburger PLoS computational biology 5 (4), e1000340, 2009 | 164 | 2009 |
| CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms C Terfve, T Cokelaer, D Henriques, A MacNamara, E Goncalves, ... BMC systems biology 6 (1), 133, 2012 | 148 | 2012 |
| Transcriptional data: a new gateway to drug repositioning? F Iorio, T Rittman, H Ge, M Menden, J Saez-Rodriguez Drug discovery today 18 (7-8), 350-357, 2013 | 147 | 2013 |
Leonidas AlexopoulosMechanical Engineering, National Technical University of AthensVerified email at mail.ntua.gr
