Clifton E Barry III
Clifton E Barry III
NIAID
Verified email at niaid.nih.gov - Homepage
TitleCited byYear
Improved physical stability of an Antibody Drug Conjugate using Host-Guest chemistry
S Sonzini, ML Greco, T Cailleau, LR Adams, LA Masterson, ...
Bioconjugate Chemistry, 2019
2019
TR1801‐ADC: A highly potent cMet antibody‐drug conjugate with high activity in patient‐derived xenograft models of solid tumors
M Gymnopoulos, O Betancourt, V Blot, R Fujita, D Galvan, V Lieuw, ...
Molecular oncology, 2019
2019
Changes in inflammatory protein and lipid mediator profiles persist after antitubercular treatment of pulmonary and extrapulmonary tuberculosis: A prospective cohort study
CL Vinhaes, D Oliveira-de-Souza, PS Silveira-Mattos, B Nogueira, R Shi, ...
Cytokine 123, 154759, 2019
12019
Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development
T Beites, K O’Brien, D Tiwari, CA Engelhart, S Walters, J Andrews, ...
Nature communications 10 (1), 1-12, 2019
2019
C4-Phenylthio β-lactams: Effect of the chirality of the β-lactam ring on antimicrobial activity
R Kuskovsky, D Lloyd, K Arora, BJ Plotkin, JM Green, HI Boshoff, ...
Bioorganic & medicinal chemistry 27 (20), 115050, 2019
2019
Inhibition of CorA-Dependent Magnesium Homeostasis Is Cidal in Mycobacterium tuberculosis
Y Park, YM Ahn, S Jonnala, S Oh, JM Fisher, MB Goodwin, TR Ioerger, ...
Antimicrobial agents and chemotherapy 63 (10), e01006-19, 2019
2019
Targeting of Fumarate Hydratase from Mycobacterium tuberculosis Using Allosteric Inhibitors with a Dimeric-Binding Mode
AJ Whitehouse, MDJ Libardo, M Kasbekar, PD Brear, G Fischer, ...
Journal of medicinal chemistry, 2019
12019
Mode-of-action profiling reveals glutamine synthetase as a collateral metabolic vulnerability of M. tuberculosis to bedaquiline
Z Wang, V Soni, G Marriner, T Kaneko, HIM Boshoff, CE Barry, KY Rhee
Proceedings of the National Academy of Sciences 116 (39), 19646-19651, 2019
2019
The Lancet Respiratory Medicine Commission: 2019 update: epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant and incurable tuberculosis
K Dheda, T Gumbo, G Maartens, KE Dooley, M Murray, J Furin, ...
The Lancet Respiratory Medicine 7 (9), 820-826, 2019
2019
TR1801-ADC, an optimized anti cMet PBD ADC with high efficacy in solid tumors of the GI tract and head & neck cancer
M Gymnopoulos, O Betancourt, V Blot, R Fujita, D Ly, S Nguyen, ...
Cancer Research 79 (13 Supplement), 225-225, 2019
2019
Synthesis and evaluation of pyrrolobenzodiazepine dimer antibody-drug conjugates with dual β-glucuronide and dipeptide triggers
SJ Gregson, AM Barrett, NV Patel, GD Kang, D Schiavone, E Sult, ...
European Journal of Medicinal Chemistry, 2019
12019
Molecular degree of perturbation of plasma inflammatory markers associated with tuberculosis reveals distinct disease profiles between Indian and Chinese populations
D Oliveira-de-Souza, CL Vinhaes, MB Arriaga, NP Kumar, ...
Scientific reports 9 (1), 8002, 2019
12019
A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis
P MacGregor, AL Gonzalez-Munoz, F Jobe, MC Taylor, S Rust, ...
PLoS neglected tropical diseases 13 (5), e0007373, 2019
12019
Linezolid resistance in patients with drug-resistant TB and treatment failure in South Africa
S Wasserman, G Louw, L Ramangoaela, G Barber, C Hayes, SV Omar, ...
Journal of Antimicrobial Chemotherapy, 2019
2019
Tuberculosis drugs’ distribution and emergence of resistance in patient’s lung lesions: A mechanistic model and tool for regimen and dose optimization
N Strydom, SV Gupta, WS Fox, LE Via, H Bang, M Lee, S Eum, TS Shim, ...
PLoS medicine 16 (4), e1002773, 2019
122019
Molecular degree of perturbation of plasma inflammatory markers associated with tuberculosis reveals distinct disease profiles between Indian and Chinese populations.
DO Souza, CL Vinhaes, MB Arriaga, NP Kumar, JMC Angulo, R Shi, ...
Nature Research, 2019
2019
A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography …
ST Malherbe, P Dupont, I Kant, P Ahlers, M Kriel, AG Loxton, RY Chen, ...
EJNMMI research 8 (1), 55, 2018
12018
Structures of DPAGT1 explain glycosylation disease mechanisms and advance TB antibiotic design
YY Dong, H Wang, ACW Pike, SA Cochrane, S Hamedzadeh, ...
Cell 175 (4), 1045-1058. e16, 2018
122018
Discovery and Structure–Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2 …
S Oh, Y Park, CA Engelhart, JB Wallach, D Schnappinger, K Arora, ...
Journal of medicinal chemistry 61 (22), 9952-9965, 2018
42018
The present state of the tuberculosis drug development pipeline
MDJ Libardo, HIM Boshoff, CE Barry III
Current opinion in pharmacology 42, 81-94, 2018
132018
The system can't perform the operation now. Try again later.
Articles 1–20