| Macrophage activation and polarization: nomenclature and experimental guidelines PJ Murray, JE Allen, SK Biswas, EA Fisher, DW Gilroy, S Goerdt, ... Immunity 41 (1), 14-20, 2014 | 2389 | 2014 |
| Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue JPJ Saeij, S Coller, JP Boyle, ME Jerome, MW White, JC Boothroyd Nature 445 (7125), 324, 2007 | 510 | 2007 |
| Polymorphic secreted kinases are key virulence factors in toxoplasmosis JPJ Saeij, JP Boyle, S Coller, S Taylor, LD Sibley, ET Brooke-Powell, ... Science 314 (5806), 1780-1783, 2006 | 500 | 2006 |
| Strain-specific activation of the NF-κB pathway by GRA15, a novel Toxoplasma gondii dense granule protein EE Rosowski, D Lu, L Julien, L Rodda, RA Gaiser, KDC Jensen, JPJ Saeij Journal of Experimental Medicine 208 (1), 195-212, 2011 | 298 | 2011 |
| Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host JPJ Saeij, JP Boyle, JC Boothroyd Trends in parasitology 21 (10), 476-481, 2005 | 271 | 2005 |
| A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes SM Sidik, D Huet, SM Ganesan, MH Huynh, T Wang, AS Nasamu, P Thiru, ... Cell 166 (6), 1423-1435. e12, 2016 | 243 | 2016 |
| Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence ML Reese, GM Zeiner, JPJ Saeij, JC Boothroyd, JP Boyle Proceedings of the National Academy of Sciences 108 (23), 9625-9630, 2011 | 202 | 2011 |
| Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains JPJ Saeij, JP Boyle, ME Grigg, G Arrizabalaga, JC Boothroyd Infection and immunity 73 (2), 695-702, 2005 | 186 | 2005 |
| Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulence IJ Blader, JP Saeij Apmis 117 (5‐6), 458-476, 2009 | 185 | 2009 |
| Toxoplasma gondii effectors are master regulators of the inflammatory response MB Melo, KDC Jensen, JPJ Saeij Trends in parasitology 27 (11), 487-495, 2011 | 160 | 2011 |
| The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response W Niedelman, DA Gold, EE Rosowski, JK Sprokholt, D Lim, AF Arenas, ... PLoS pathogens 8 (6), e1002784, 2012 | 158 | 2012 |
| Molecular and functional characterization of carp TNF: a link between TNF polymorphism and trypanotolerance? JPJ Saeij, RJM Stet, BJ De Vries, WB Van Muiswinkel, GF Wiegertjes Developmental & Comparative Immunology 27 (1), 29-41, 2003 | 150 | 2003 |
| Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation KDC Jensen, Y Wang, EDT Wojno, AJ Shastri, K Hu, L Cornel, E Boedec, ... Cell host & microbe 9 (6), 472-483, 2011 | 143 | 2011 |
| Molecular and functional characterization of a fish inducible-type nitric oxide synthase JPJ Saeij, RJM Stet, A Groeneveld, LBM Verburg-van Kemenade, ... Immunogenetics 51 (4-5), 339-346, 2000 | 136 | 2000 |
| Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii JP Boyle, B Rajasekar, JPJ Saeij, JW Ajioka, M Berriman, I Paulsen, ... Proceedings of the National Academy of Sciences 103 (27), 10514-10519, 2006 | 122 | 2006 |
| Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii G Gorfu, KM Cirelli, MB Melo, K Mayer-Barber, D Crown, BH Koller, ... MBio 5 (1), e01117-13, 2014 | 119 | 2014 |
| The immune response of carp to Trypanoplasma borreli: kinetics of immune gene expression and polyclonal lymphocyte activation JPJ Saeij, BJ De Vries, GF Wiegertjes Developmental & Comparative Immunology 27 (10), 859-874, 2003 | 111 | 2003 |
| Daily handling stress reduces resistance of carp to Trypanoplasma borreli: in vitro modulatory effects of cortisol on leukocyte function and apoptosis JPJ Saeij, LBM Verburg-van Kemenade, WB Van Muiswinkel, ... Developmental & Comparative Immunology 27 (3), 233-245, 2003 | 110 | 2003 |
| Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes H Lorenzi, A Khan, MS Behnke, S Namasivayam, LS Swapna, ... Nature communications 7, 10147, 2016 | 106 | 2016 |
| The Toxoplasma dense granule proteins GRA17 and GRA23 mediate the movement of small molecules between the host and the parasitophorous vacuole DA Gold, AD Kaplan, A Lis, GCL Bett, EE Rosowski, KM Cirelli, ... Cell host & microbe 17 (5), 642-652, 2015 | 104 | 2015 |
