| Regulation of intestinal α-defensin activation by the metalloproteinase matrilysin in innate host defense CL Wilson, AJ Ouellette, DP Satchell, T Ayabe, YS López-Boado, ... Science 286 (5437), 113-117, 1999 | 1163 | 1999 |
| Urinary tract infections: epidemiology, mechanisms of infection and treatment options AL Flores-Mireles, JN Walker, M Caparon, SJ Hultgren Nature reviews microbiology 13 (5), 269-284, 2015 | 1042 | 2015 |
| Intracellular bacterial biofilm-like pods in urinary tract infections GG Anderson, JJ Palermo, JD Schilling, R Roth, J Heuser, SJ Hultgren Science 301 (5629), 105-107, 2003 | 1001 | 2003 |
| Role of Escherichia coli curli operons in directing amyloid fiber formation MR Chapman, LS Robinson, JS Pinkner, R Roth, J Heuser, M Hammar, ... Science 295 (5556), 851-855, 2002 | 971 | 2002 |
| Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli MA Mulvey, YS Lopez-Boado, CL Wilson, R Roth, WC Parks, J Heuser, ... Science 282 (5393), 1494-1497, 1998 | 963 | 1998 |
| Type 1 pilus‐mediated bacterial invasion of bladder epithelial cells JJ Martinez, MA Mulvey, JD Schilling, JS Pinkner, SJ Hultgren The EMBO journal 19 (12), 2803-2812, 2000 | 703 | 2000 |
| Establishment of a persistent Escherichia coli reservoir during the acute phase of a bladder infection MA Mulvey, JD Schilling, SJ Hultgren Infection and immunity 69 (7), 4572-4579, 2001 | 691 | 2001 |
| The biology and future prospects of antivirulence therapies L Cegelski, GR Marshall, GR Eldridge, SJ Hultgren Nature Reviews Microbiology 6 (1), 17, 2008 | 686 | 2008 |
| X-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coli D Choudhury, A Thompson, V Stojanoff, S Langermann, J Pinkner, ... Science 285 (5430), 1061-1066, 1999 | 656 | 1999 |
| Prevention of mucosal Escherichia coli infection by FimH-adhesin-based systemic vaccination S Langermann, S Palaszynski, M Barnhart, G Auguste, JS Pinkner, ... Science 276 (5312), 607-611, 1997 | 592 | 1997 |
| Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis SS Justice, C Hung, JA Theriot, DA Fletcher, GG Anderson, MJ Footer, ... Proceedings of the National Academy of Sciences 101 (5), 1333-1338, 2004 | 572 | 2004 |
| Bacterial adhesins: common themes and variations in architecture and assembly GE Soto, SJ Hultgren Journal of bacteriology 181 (4), 1059-1071, 1999 | 569 | 1999 |
| Bad bugs and beleaguered bladders: interplay between uropathogenic Escherichia coli and innate host defenses MA Mulvey, JD Schilling, JJ Martinez, SJ Hultgren Proceedings of the National Academy of Sciences 97 (16), 8829-8835, 2000 | 520 | 2000 |
| Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach SL Chen, CS Hung, J Xu, CS Reigstad, V Magrini, A Sabo, D Blasiar, ... Proceedings of the National Academy of Sciences 103 (15), 5977-5982, 2006 | 513 | 2006 |
| Pilus and nonpilus bacterial adhesins: assembly and function in cell recognition SJ Hultgren, S Abraham, M Caparon, P Falk, JWS Geme III, S Normark Cell 73 (5), 887-901, 1993 | 502 | 1993 |
| Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era M Kostakioti, M Hadjifrangiskou, SJ Hultgren Cold Spring Harbor perspectives in medicine 3 (4), a010306, 2013 | 498 | 2013 |
| Detection of intracellular bacterial communities in human urinary tract infection DA Rosen, TM Hooton, WE Stamm, PA Humphrey, SJ Hultgren PLoS medicine 4 (12), e329, 2007 | 494 | 2007 |
| FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobacteriaceae CH Jones, JS Pinkner, R Roth, J Heuser, AV Nicholes, SN Abraham, ... Proceedings of the National Academy of Sciences 92 (6), 2081-2085, 1995 | 447 | 1995 |
| Structural basis of chaperone function and pilus biogenesis FG Sauer, K Fütterer, JS Pinkner, KW Dodson, SJ Hultgren, G Waksman Science 285 (5430), 1058-1061, 1999 | 434 | 1999 |
| Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract IU Mysorekar, SJ Hultgren Proceedings of the National Academy of Sciences 103 (38), 14170-14175, 2006 | 410 | 2006 |
