| Gene ontology: tool for the unification of biology M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, ... Nature genetics 25 (1), 25, 2000 | 28033* | 2000 |
| Cluster analysis and display of genome-wide expression patterns MB Eisen, PT Spellman, PO Brown, D Botstein Proceedings of the National Academy of Sciences 95 (25), 14863-14868, 1998 | 18416 | 1998 |
| Molecular portraits of human breast tumours CM Perou, T Sørlie, MB Eisen, M Van De Rijn, SS Jeffrey, CA Rees, ... nature 406 (6797), 747, 2000 | 15416* | 2000 |
| Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications T Sørlie, CM Perou, R Tibshirani, T Aas, S Geisler, H Johnsen, T Hastie, ... Proceedings of the National Academy of Sciences 98 (19), 10869-10874, 2001 | 10996 | 2001 |
| Construction of a genetic linkage map in man using restriction fragment length polymorphisms. D Botstein, RL White, M Skolnick, RW Davis American journal of human genetics 32 (3), 314, 1980 | 10988 | 1980 |
| Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling AA Alizadeh, MB Eisen, RE Davis, C Ma, IS Lossos, A Rosenwald, ... Nature 403 (6769), 503, 2000 | 10214 | 2000 |
| Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. ES Lander, D Botstein Genetics 121 (1), 185-199, 1989 | 6021 | 1989 |
| Comprehensive Identification of Cell Cycle–regulated Genes of the Yeast Saccharomyces cerevisiae by Microarray Hybridization PT Spellman, G Sherlock, MQ Zhang, VR Iyer, K Anders, MB Eisen, ... Molecular biology of the cell 9 (12), 3273-3297, 1998 | 5821 | 1998 |
| Repeated observation of breast tumor subtypes in independent gene expression data sets. T Sorlie, R Tibshirani, J Parker, T Hastie, JS Marron, A Nobel, S Deng, ... Proceedings of the National Academy of Sciences of the United States of …, 2003 | 5008 | 2003 |
| Genomic expression programs in the response of yeast cells to environmental changes AP Gasch, PT Spellman, CM Kao, O Carmel-Harel, MB Eisen, G Storz, ... Molecular biology of the cell 11 (12), 4241-4257, 2000 | 4868 | 2000 |
| The Gene Ontology (GO) database and informatics resource Gene Ontology Consortium Nucleic acids research 32 (suppl_1), D258-D261, 2004 | 3850* | 2004 |
| Exploring the new world of the genome with DNA microarrays PO Brown, D Botstein Nature genetics 21 (1s), 33, 1999 | 3154 | 1999 |
| Missing value estimation methods for DNA microarrays O Troyanskaya, M Cantor, G Sherlock, P Brown, T Hastie, R Tibshirani, ... Bioinformatics 17 (6), 520-525, 2001 | 3012 | 2001 |
| Knowledge-based analysis of microarray gene expression data by using support vector machines MPS Brown, WN Grundy, D Lin, N Cristianini, CW Sugnet, TS Furey, ... Proceedings of the National Academy of Sciences 97 (1), 262-267, 2000 | 2919 | 2000 |
| Advanced bacterial genetics: a manual for genetic engineering RW Davis, D Botstein | 2688 | 1980 |
| Systematic variation in gene expression patterns in human cancer cell lines DT Ross, U Scherf, MB Eisen, CM Perou, C Rees, P Spellman, V Iyer, ... Nature genetics 24 (3), 227, 2000 | 2440 | 2000 |
| The transcriptional program in the response of human fibroblasts to serum VR Iyer, MB Eisen, DT Ross, G Schuler, T Moore, JCF Lee, JM Trent, ... Science 283 (5398), 83-87, 1999 | 2389 | 1999 |
| The transcriptional program of sporulation in budding yeast S Chu, J DeRisi, M Eisen, J Mulholland, D Botstein, PO Brown, ... Science 282 (5389), 699-705, 1998 | 2157 | 1998 |
| Singular value decomposition for genome-wide expression data processing and modeling O Alter, PO Brown, D Botstein Proceedings of the National Academy of Sciences 97 (18), 10101-10106, 2000 | 2152 | 2000 |
| Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data E Segal, M Shapira, A Regev, D Pe'er, D Botstein, D Koller, N Friedman Nature genetics 34 (2), 166, 2003 | 1916 | 2003 |
